Sulfobetaines

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Example of a sulfobetaine.

Sulfobetaines , also known as sultaines, are surface-active substances and count among the ampholytes . This zwitterion compounds structurally similar to betaines containing instead of the carboxylate group (COO - ) but one, mostly as sulfopropyl present, SO 3 - radical.

use

Sulfobetaines play a certain role as amphoteric surfactants in shampoos and foam baths. In biochemistry, sulfobetaines are used to dissolve proteins , e.g. B. in 2D gel electrophoresis , and for non-stick coating of surfaces such. B. with quantum dots .

Individual evidence

  1. ^ Brockhaus ABC chemistry. VEB FA Brockhaus Verlag Leipzig 1965, p. 1363.
  2. ↑ a b Otto-Albrecht Neumüller (Ed.): Römpps Chemie-Lexikon. Volume 5: Pl-S. 8th revised and expanded edition. Franckh'sche Verlagshandlung, Stuttgart 1987, ISBN 3-440-04515-3 , p. 4058.
  3. ↑ L. Vuillard, N. Marret, T. Rabilloud: Enhancing protein solubilization with nondetergent sulfobetaines. In: Electrophoresis. Volume 16, Number 3, March 1995, pp. 295-297, PMID 7607159 .
  4. ↑ C. Tastet, S. Charmont, M. Chevallet, S. Luche, T. Rabilloud: Structure-efficiency relationships of zwitterionic detergents as protein solubilizers in two-dimensional electrophoresis. In: Proteomics. Volume 3, Number 2, February 2003, pp. 111-121, doi : 10.1002 / pmic.200390019 . PMID 12601803 .
  5. ^ S. Luche, V. Santoni, T. Rabilloud: Evaluation of nonionic and zwitterionic detergents as membrane protein solubilizers in two-dimensional electrophoresis. In: Proteomics. Volume 3, Number 3, March 2003, pp. 249-253, doi : 10.1002 / pmic.200390037 . PMID 12627377 .
  6. ^ E. Muro, T. Pons, N. Lequeux, A. Fragola, N. Sanson, Z. Lenkei, B. Dubertret: Small and stable sulfobetaine zwitterionic quantum dots for functional live-cell imaging. In: Journal of the American Chemical Society. Volume 132, Number 13, April 2010, pp. 4556-4557, doi : 10.1021 / ja1005493 . PMID 20235547 .