Michio Ui

Michio Ui ( Japanese 宇井理生 , Ui Michio ; born February 20, 1933 in Tokyo ) is a Japanese biochemist .

Career

He was a professor at the University of Tokyo (Department of Physiological Chemistry) and from 1995 to 2000 director of the Tokyo Metropolitan Institute of Medical Science, founded in 1975. He also held an honorary professorship in the Faculty of Medicine at the University of Tokyo.

In the early 1980s, Ui isolated a component of whooping cough toxin (PTX, called IAP, islet activating protein , by Ui and co-workers at the time ), which played an important role in clarifying the role of G proteins in signal transmission via receptors in the cell membrane Cell inside played. In particular, he and his colleagues were able to show that IAP counteracted the inhibitory role of hormones in the release of adenylyl cyclases . At that time he partly worked with his student Toshiaki Katada .

In 1991 he received the Paul Ehrlich and Ludwig Darmstaedter Prize and the "Imperial Prize" from the Japanese Academy of Sciences .

Individual evidence

↑ 宇井理生 . In: デジタル版日本人名大辞典 + Plus at kotobank.jp. January 20, 2009, accessed March 6, 2012 (Japanese, online version by Nihon Jinmei Daijiten . Kodansha).
^ History of the Tokyo Metropolitan Institute of Medical Science ( Memento December 9, 2010 in the Internet Archive )
↑ Lutz Birnbaumer The discovery of signal transduction by G proteins. A personal account and an overview of the initial findings and understanding that led to our present , Biochim. Biophys. Acta , April 2007, 1768 (4), pp. 756–771, PMC 1894990 (free full text)

personal data
SURNAME	Ui, Michio
ALTERNATIVE NAMES	宇井理生 (Japanese)
BRIEF DESCRIPTION	Japanese biochemist
DATE OF BIRTH	February 20, 1933
PLACE OF BIRTH	Tokyo

[1] 宇井理生 . In: デジタル版日本人名大辞典 + Plus at kotobank.jp. January 20, 2009, accessed March 6, 2012 (Japanese, online version by Nihon Jinmei Daijiten . Kodansha).

[2] History of the Tokyo Metropolitan Institute of Medical Science ( Memento December 9, 2010 in the Internet Archive )

[3] Lutz Birnbaumer The discovery of signal transduction by G proteins. A personal account and an overview of the initial findings and understanding that led to our present , Biochim. Biophys. Acta , April 2007, 1768 (4), pp. 756–771, PMC 1894990 (free full text)