Urochrome
As Urochrome all in are urine occurring metabolites indicated that color it. They are often summarized as urochrome without defining exactly what materials they are made of. Part of the urochromes make up intermediate products of the build-up and breakdown of the red blood pigment, hemoglobin . These bile pigments are porphyrins such as urobilins or biliverdin .
Many other metabolic products, as well as ingested foods and drugs, affect urine color . It can vary considerably even in healthy people. In addition to the influence of food, it is mainly based on the fluid balance: If we drink a lot of fluids, the urine becomes relatively dilute and its color is almost water-white or pale yellow. If we take in little fluids or lose a lot of fluids (diarrhea, sweating, e.g. during exercise), the body has to save water and will only excrete very little urine. The urine is then very concentrated and dark yellow.
A distinction is made between the urine pigment as a red and yellow fraction (urobilin or urochromium fraction) and as uncolored protein acids ( histidine fraction , including uro-rose ).
The yellow dyes, which are produced oxidatively from urochromogens (class of oxyprotein acids ) (urochromes A and B; 95 percent of the urine color value), are - as hemoglobin breakdown products - increased in certain diseases and represent the actual substrate of the diazo reactions, form so-called Residual dye group together with urobilin and uroerythrin the normal urine color.
Individual evidence
- ↑ S. Viswanathan: Urine bag as a modern day matula. In: ISRN nephrology. Volume 2013, 2013, p. 215690, ISSN 2314-405X . doi : 10.5402 / 2013/215690 . PMID 24959539 . PMC 4045424 (free full text).