Wolfgang Stremmel

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Wolfgang Stremmel (born April 22, 1952 in Cologne ) is a German physician ( internal medicine , gastroenterology ).

Stremmel studied medicine at the University of Cologne from 1970 with his doctorate and license to practice medicine in 1977 (dissertation: bis (monoacylglycerin) phosphate: a "marker" phosphatide of secondary lysosomes), then was an assistant at the Institute for Physiological Chemistry in Cologne and from 1978 at the University Hospital Düsseldorf . 1980 to 1982 he was a visiting researcher at the Mount Sinai School of Medicine in New York. In 1984 he became a specialist in internal medicine. In 1985 he completed his habilitation in Düsseldorf (with the thesis: Receptor-mediated transport processes - studies on the hepatocellular transport of bilirubin and fatty acids as well as on the intestinal fatty acid absorption ), became a university lecturer there and was project manager of the research group Mechanisms of Liver Damage from 1989 to 1996 . In 1987 he became a senior physician in the gastroenterology department at the Center for Internal Medicine at the University Clinics in Düsseldorf, an adjunct professor in 1989 and professor in 1991. In 1994 he became professor and medical director of the Medical Clinic and Polyclinic, Department of Internal Medicine IV at the Ruprecht-Karls-Universität Heidelberg (gastroenterology, infectious diseases, poisoning). In 2018 Stremmel retired .

Among other things, he dealt with fatty liver hepatitis and its pathogenesis, therapy of hepatitis with phosphatidylcholine, therapy of chronic inflammatory bowel diseases with phosphatidylcholine, iron metabolism / hemochromatosis, copper metabolism ( Wilson's disease ), fatty acid metabolism.

He researched the mode of action of the body's own phosphatidylcholine in the reconstruction of the protective layer of mucus in the large intestine, which was used for a drug against ulcerative colitis (Lipid Therapeutics, Heidelberg). Stremmel also accompanied the clinical studies (from 2005), which led to a first publication in 2007 and subsequent phase II studies. One of the main problems was to package the phosphatidylcholine in such a way that it was not absorbed in the upper part of the small intestine, but reached the large intestine.

In 1989 Stremmel received the Gottfried Wilhelm Leibniz Prize . In 1985 he received the Thannhauser Prize of the German Society for Digestive and Metabolic Diseases and in 1988 the European Price of Gastroenterology . In 2006 he received an honorary doctorate from the University of Tbilisi.

Fonts

  • with Harald Hefter, Cathrin Smolarek: Wilson's disease: pathogenesis, symptoms, diagnosis and therapy of the copper storage disease , Lobenfeld near Heidelberg: Hefter 2000

Web links

Individual evidence

  1. ↑ Dates of birth according to Kürschner, Scholars Calendar 2009
  2. ↑ Julia Bird: The renowned internist Professor Dr. Wolfgang Stremmel is retiring. Heidelberg University Hospital, press release from March 29, 2018 from Informationsdienst Wissenschaft (idw-online.de), accessed on March 29, 2018.
  3. ↑ W. Stremmel, U. Merle, A. Zahn, F. Autschbach, U. Hinz, R. Ehehalt: Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis , in: Gut, Volume 54, 2005, Issue 7, p. 966-971.
  4. ^ W. Stremmel, R. Ehehalt, F. Autschbach, M. Karner, Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial . Annals Intern. Med., Volume 147, 2007, Issue 9, pp. 603-610
  5. ↑ The mucous barrier in the large intestine is being rebuilt , press release Heidelberg University Hospital March 18, 2010
personal data
SURNAME Stremmel, Wolfgang
BRIEF DESCRIPTION German physicians (internal medicine, gastroenterology)
DATE OF BIRTH April 22, 1952
PLACE OF BIRTH Cologne