Camptotheca: Difference between revisions
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*''Camptotheca lowreyana'' S.Y.Li |
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The bark and stems of ''C. acuminata'' contain the [[alkaloid]] [[camptothecin]]. Several chemical [[derivative (chemistry)|derivatives]] of camptothecin are under investigation for or used as drugs for cancer treatment, including [[irinotecan]], [[topotecan]], [[rubitecan]]. |
The bark and stems of ''C. acuminata'' contain the [[alkaloid]] [[camptothecin]]. Several chemical [[derivative (chemistry)|derivatives]] of camptothecin are under investigation for or used as drugs for cancer treatment, including [[irinotecan]], [[topotecan]], [[rubitecan]].<ref>{{Cite book| author = G. Samuelsson| title = Drugs of Natural Origin: a Textbook of Pharmacognosy | year = 2004 | publisher = Swedish pharmaceutical press | location = Stokkholm | edition = 5| isbn = 91-974318-4-2 }}</ref> |
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''C. acuminata'' also contains the chemical compounds [[trifolin]] and [[hyperoside]].<ref>{{ cite journal | title = Antifungal Activity of Camptothecin, Trifolin, and Hyperoside Isolated from ''Camptotheca acuminata'' | author = Li, S.; Zhang, Z.; Cain, A.; Wang, B.; Long, M.; Taylor, J. | journal = Journal of Agricultural and Food Chemistry | year = 2005 | volume = 53 | issue = 1 | pages = 32–37 | doi = 10.1021/jf0484780 | pmid = 15631505 }}</ref> |
''C. acuminata'' also contains the chemical compounds [[trifolin]] and [[hyperoside]].<ref>{{ cite journal | title = Antifungal Activity of Camptothecin, Trifolin, and Hyperoside Isolated from ''Camptotheca acuminata'' | author = Li, S.; Zhang, Z.; Cain, A.; Wang, B.; Long, M.; Taylor, J. | journal = Journal of Agricultural and Food Chemistry | year = 2005 | volume = 53 | issue = 1 | pages = 32–37 | doi = 10.1021/jf0484780 | pmid = 15631505 }}</ref> |
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Revision as of 13:50, 10 January 2013
| Happy tree | |
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| Cancer Tree, Camptotheca acuminata | |
| Scientific classification | |
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| Genus: | Camptotheca |
| Species | |
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Camptotheca acuminata | |
Camptotheca (happy tree, cancer tree, or tree of life) is a genus of medium-sized deciduous trees growing to 20 metres (66 ft) tall, native to southern China and Tibet. The genus is usually included in the tupelo family Nyssaceae, but sometimes included (with the tupelos) in the dogwood family Cornaceae.
The name "happy tree" is a direct translation of the Chinese name xi shu (Simplified Chinese:喜树).
There are two species:
- Camptotheca acuminata Decne.
- Camptotheca lowreyana S.Y.Li
The bark and stems of C. acuminata contain the alkaloid camptothecin. Several chemical derivatives of camptothecin are under investigation for or used as drugs for cancer treatment, including irinotecan, topotecan, rubitecan.[1]
C. acuminata also contains the chemical compounds trifolin and hyperoside.[2]
References
- ^ G. Samuelsson (2004). Drugs of Natural Origin: a Textbook of Pharmacognosy (5 ed.). Stokkholm: Swedish pharmaceutical press. ISBN 91-974318-4-2.
- ^ Li, S.; Zhang, Z.; Cain, A.; Wang, B.; Long, M.; Taylor, J. (2005). "Antifungal Activity of Camptothecin, Trifolin, and Hyperoside Isolated from Camptotheca acuminata". Journal of Agricultural and Food Chemistry. 53 (1): 32–37. doi:10.1021/jf0484780. PMID 15631505.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
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