Streptomyces toxytricini: Difference between revisions
Content deleted Content added
Change Taxobox to Speciesbox using Taxoboxalyzer |
|||
| (9 intermediate revisions by 8 users not shown) | |||
| Line 1: | Line 1: | ||
{{Short description|Species of bacterium}} |
|||
{{italic title}} |
|||
{{Speciesbox |
|||
{{Taxobox |
|||
| ⚫ | |||
| color = lightgrey |
|||
| ⚫ | |||
| ⚫ | |||
| domain = [[Bacterium|Bacteria]] |
|||
| phylum = [[Actinobacteria]] |
|||
| ordo = [[Actinomycetales]] |
|||
| familia = [[Streptomycetaceae]] |
|||
| genus = ''[[Streptomyces]]'' |
|||
| species = '''''S. toxytricini''''' |
|||
| binomial = ''Streptomyces toxytricini'' |
|||
| ⚫ | |||
}} |
}} |
||
'''''Streptomyces toxytricini''''' is a [[Gram-positive]] [[bacteria|bacterium]] belonging to the [[genus]] ''[[Streptomyces]]''. It produces the [[pancreatic lipase]] [[enzyme inhibitor|inhibitor]] [[lipstatin]],<ref>{{cite journal |vauthors=Weibel E, Hadvary P, Hochuli E, Kupfer E, Lengsfeld H |title=Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity |journal=J Antibiot (Tokyo) |volume=40 |issue=8 |pages=1081–5 |year=1987 |pmid=3680018 |doi=10.7164/antibiotics.40.1081}}</ref> of which the antiobesity drug [[orlistat]] is a derivative.<ref name="OriginalSynth">{{cite journal |vauthors=Barbier P, Schneider F | title = Syntheses of tetrahydrolipstatin and absolute configuration of tetrahydrolipstatin and lipstatin | journal = Helvetica Chimica Acta | volume = 70 | issue = 1 | pages = 196–202 | year = 1987 | doi = 10.1002/hlca.19870700124}}</ref> |
'''''Streptomyces toxytricini''''' is a [[Gram-positive]] [[bacteria|bacterium]] belonging to the [[genus]] ''[[Streptomyces]]''. It produces the [[pancreatic lipase]] [[enzyme inhibitor|inhibitor]] [[lipstatin]],<ref>{{cite journal |vauthors=Weibel E, Hadvary P, Hochuli E, Kupfer E, Lengsfeld H |title=Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity |journal=J Antibiot (Tokyo) |volume=40 |issue=8 |pages=1081–5 |year=1987 |pmid=3680018 |doi=10.7164/antibiotics.40.1081|doi-access=free }}</ref> of which the antiobesity drug [[orlistat]] is a derivative.<ref name="OriginalSynth">{{cite journal |vauthors=Barbier P, Schneider F | title = Syntheses of tetrahydrolipstatin and absolute configuration of tetrahydrolipstatin and lipstatin | journal = Helvetica Chimica Acta | volume = 70 | issue = 1 | pages = 196–202 | year = 1987 | doi = 10.1002/hlca.19870700124}}</ref> |
||
== References == |
== References == |
||
| Line 18: | Line 11: | ||
== Further reading == |
== Further reading == |
||
* {{cite journal|last1=Zhu|first1=Tingheng|last2=Wang|first2=Lingfei|last3=Wang|first3=Weixia|last4=Hu|first4=Zhongce|last5=Yu|first5=Meilan|last6=Wang|first6=Kun|last7=Cui|first7=Zhifeng|title=Enhanced production of lipstatin from Streptomyces toxytricini by optimizing fermentation conditions and medium|journal=Journal of General and Applied Microbiology|date=April 3, 2014|volume=60|issue=3|pages=106–111|doi=10.2323/jgam.60.106|pmid=25008166}} |
* {{cite journal|last1=Zhu|first1=Tingheng|last2=Wang|first2=Lingfei|last3=Wang|first3=Weixia|last4=Hu|first4=Zhongce|last5=Yu|first5=Meilan|last6=Wang|first6=Kun|last7=Cui|first7=Zhifeng|title=Enhanced production of lipstatin from Streptomyces toxytricini by optimizing fermentation conditions and medium|journal=Journal of General and Applied Microbiology|date=April 3, 2014|volume=60|issue=3|pages=106–111|doi=10.2323/jgam.60.106|pmid=25008166|doi-access=free}} |
||
==External links== |
|||
*[http://bacdive.dsmz.de/index.php?search=16057&submit=Search Type strain of ''Streptomyces toxytricini'' at Bac''Dive'' - the Bacterial Diversity Metadatabase] |
|||
{{Taxonbar|from=Q5850486}} |
|||
[[Category:Streptomyces|toxytricini]] |
[[Category:Streptomyces|toxytricini]] |
||
[[Category:Bacteria described in 1957]] |
|||
Latest revision as of 23:24, 12 April 2024
| Streptomyces toxytricini | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Actinomycetota |
| Class: | Actinomycetia |
| Order: | Streptomycetales |
| Family: | Streptomycetaceae |
| Genus: | Streptomyces |
| Species: | S. toxytricini
|
| Binomial name | |
| Streptomyces toxytricini Preobrazhenskaya & Sveshnikova 1957
| |
Streptomyces toxytricini is a Gram-positive bacterium belonging to the genus Streptomyces. It produces the pancreatic lipase inhibitor lipstatin,[1] of which the antiobesity drug orlistat is a derivative.[2]
References[edit]
- ^ Weibel E, Hadvary P, Hochuli E, Kupfer E, Lengsfeld H (1987). "Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity". J Antibiot (Tokyo). 40 (8): 1081–5. doi:10.7164/antibiotics.40.1081. PMID 3680018.
- ^ Barbier P, Schneider F (1987). "Syntheses of tetrahydrolipstatin and absolute configuration of tetrahydrolipstatin and lipstatin". Helvetica Chimica Acta. 70 (1): 196–202. doi:10.1002/hlca.19870700124.
Further reading[edit]
- Zhu, Tingheng; Wang, Lingfei; Wang, Weixia; Hu, Zhongce; Yu, Meilan; Wang, Kun; Cui, Zhifeng (April 3, 2014). "Enhanced production of lipstatin from Streptomyces toxytricini by optimizing fermentation conditions and medium". Journal of General and Applied Microbiology. 60 (3): 106–111. doi:10.2323/jgam.60.106. PMID 25008166.
External links[edit]
 | This Streptomyces-related article is a stub. You can help Wikipedia by expanding it. |