1-deoxy- D- xylulose-5-phosphate synthase

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1-deoxy-D-xylulose-5-phosphate synthase

Existing structural data : 2O1S

Mass / length primary structure 621 amino acids
Identifier
Gene name (s) DOXP / DXS
External IDs
Enzyme classification
EC, category 2.2.1.7 transferase
Substrate Pyruvate, glyceraldehyde-3-phosphate (G3P)
Products 1-deoxy- D -xylulose-5-phosphate, carbon dioxide
Occurrence
Parent taxon Plants, protists

The 1-deoxy- D -xylulose-5-phosphate synthase (DOXP) is an enzyme from the methylerythritol phosphate pathway (also DOXP pathway) in plants and protists , which the conversion of

Pyruvate + glyceraldehyde-3-phosphate 1-deoxy- D - xylulose-5-phosphate + CO 2

catalyzed. DOXP is one of the transferases . The name DXP-Synthase (DXS) can be used synonymously.

Web links

Individual evidence

  1. SN Moreno, ZH Li: Anti-infectives targeting the isoprenoid pathway of Toxoplasma gondii. In: Expert Opinion on Therapeutic Targets . Volume 12, number 3, March 2008, pp. 253-263, doi : 10.1517 / 14728222.12.3.253 . PMID 18269336 .
  2. E. Cordoba, M. Salmi, P. León: Unraveling the regulatory mechanisms that modulate the MEP pathway in higher plants. In: Journal of experimental botany. Volume 60, number 10, 2009, pp. 2933-2943, doi : 10.1093 / jxb / erp190 . PMID 19584121 .