Drug Therapy Safety

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Drug therapy safety ( AMTS abbreviation ) means the safe use of drugs beyond the pure instructions for use or intake, with additional consideration of the correct prescription, its correct implementation and taking into account the adherence to therapy . The aim is to optimally organize the medication process with the aim of avoiding undesirable drug events based on medication errors and thus minimizing risks during therapy. According to the Federal Ministry of Health, AMTS should "be an integral part of medicine and pharmacy".

meaning

Insufficiently controlled drug therapy leads to avoidable disease risks. They go back to medication errors, which could often be avoided. Medication errors and the resulting preventable drug adverse events are indeed common. A study from 2003 assumes around 28,000 preventable deaths in this regard in Germany. Errors in prescribing medication occur particularly frequently, followed by errors in use or ingestion. According to estimates by the WHO , up to 10% of all hospital admissions in industrialized countries are due to adverse drug events.

The World Health Organization (WHO) emphasizes in its report "Research on Patient Safety" the need for research and intervention in this area. For Germany, the Federal Ministry of Health bundles the relevant measures in its action plan to improve the AMTS.

The Federal Institute for Drugs and Medical Devices (BfArM) started the study in November 2014: "Medication errors as a cause of hospital admissions". It is estimated that there are 500,000 hospital emergency admissions in Germany every year due to preventable medication errors.

Every year, 1.4 billion pharmaceuticals are dispensed across Germany, of which more than 600 million are prescription-free but pharmacy-only. Often times, patients have more than one prescribing doctor. In all cases, however, your drugs go through the hands of a pharmacist and his pharmaceutical staff before they reach the patient or consumer. Germany's pharmacies have around a billion patient contacts every year.

Use of information technology

The use of information technology as an approach to improving AMTS is currently being discussed more and more. So z. For example, electronic prescription systems use decision-making functions to indicate incorrect dosages or duplicate prescriptions, automatic dispensing systems compile the prescribed medication correctly, mobile applications remind the patient to take them, and critical incident reporting systems enable medication errors to be reported. Examples of information technologies to support the medication process and to reduce medication errors and thus improve drug therapy safety are:

Individual evidence

  1. ↑ a b Action Plan 2013–2015 of the Ministry of Health to improve drug therapy safety in Germany. ( Memento of October 25, 2013 in the Internet Archive ) p. 4.
  2. ↑ J. Schnurrer, J. Frölich: On the frequency and avoidability of fatal adverse drug reactions. In: Internist. 44, 2003, pp. 889-895.
  3. ↑ DW Bates, DJ Cullen, N. Laird, LA Petersen, SD Small, D. Servi, G. Laffel, BJ Sweitzer, BF Shea, R. Hallisey et al .: Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. In: JAMA. 274 (1), Jul 5, 1995, pp. 29-34.
  4. ↑ Ashish Jha: Summary of the evidence on patient safety: implications for research. ISBN 978-92-4-159654-1 .
  5. ↑ Medication errors as the cause of hospital admissions: Federal Institute for Drugs and Medical Devices starts new research project. ( Memento of the original from August 18, 2016 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. BfArM press release from November 28, 2014.  @1@ 2Template: Webachiv / IABot / www.bfarm.de
  6. ↑ ABDA fact sheet: List of medications and drug therapy safety as of January 1, 2016
  7. ↑ Die Apotheke: Figures Data Facts 2016
  8. ↑ E. Ammenwerth, A. Neubert, M. Criegee-Rieck: Drug therapy safety and IT: the way to new shores - drug therapy safety and IT. In: Deutsches Ärzteblatt. 111, 26, 2014, pp. 1195-1200.
  9. ↑ a b c d e f E. Ammenwerth, AF Aly, T. Bürkle, P. Christ, H. Dormann, W. Friesdorf, C. Haas, WE Haefeli, M. Jeske, J. Kaltschmidt, K. Menges, H Möller, A. Neubert, W. Rascher, H. Reichert, J. Schuler, G. Schreier, S. Schulz, HM Seidling, W. Stühlinger, M. Criegee-Rieck: On the use of information technology to improve drug therapy safety (Memorandum AMTS-IT) . In: GMS Med Inform Biom Epidemiol. 10 (1), 2014, Doc03.
  10. ↑ D. Grandt, C. Braun, W. Hauser: Frequency, relevance, causes and strategies for avoiding medication errors. In: Journal of Gerontology and Geriatrics. 38, 2005, pp. 196-202.
  11. ^ A b Institute of Medicine Preventing Medication Errors . The National Academic Press, Washington DC 2007.
  12. ^ PM Cox, Jr., S. D'Amato, DJ Tillotson: Reducing medication errors. In: American Journal on Medical Quality. 16 (3), 2001, pp. 81-86.
  13. ↑ Wilfried von Eiff (Ed.): Patient-oriented drug supply - safety and economic efficiency of drug management. Thieme, 2011, p. 108.

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