Acidophilia (cytology, hematology)

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In cell biology and cytodiagnostics, acidophilia (from Latin acidus = sour and ancient Greek φίλος philos = friend) is the property of certain components of cells to bind “acid” dyes . These are dyes that are ionic, i.e. dissociate , and in which the anion (negatively charged ion ) is the dye. For example, eosin is an “acidic” dye. The cell components concerned are basic (positively charged) and are referred to as acidophilic .

In hematology , the term acidophilia is used for leukocytes that bind “acid” dyes. For the differentiation of the leukocytes, eosin is mainly used as an "acidic" dye. It is bound by components in the cytoplasm of certain leukocytes and turns them bright red; these leukocytes are known as eosinophils .

See also

Individual evidence

  1. Maria Mulisch, Ulrich Welsch (ed.): Romeis - microscopic technology . 19th edition. Springer Spectrum, Berlin, Heidelberg 2015, ISBN 978-3-642-55189-5 , pp. 176 ( limited preview in Google Book search).