Adie syndrome

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Classification according to ICD-10
H57 Other affections of the eye and the appendages
H57.0 Pupillary dysfunction
ICD-10 online (WHO version 2019)

The Adie syndrome consists of pupillotonia (delayed pupillary reaction ), accommodation (delayed accommodation ) and the extensive lack of reflexes ( areflexia ), v. a. in the area of ​​the legs. The absence of the triceps surae reflex (Achilles tendon reflex) or the patellar tendon reflex is typical here . It is named after the neurologist William John Adie .

The cause of the syndrome is unclear; it may be caused by a dysfunction of the ciliary ganglion . Changes (possibly inflammatory) in the diencephalon and / or mesencephalon are also discussed. The onset of the disease is in adolescence and middle adulthood. The eye symptoms usually appear on one side at first, and later on both sides.

The combination of Adie syndrome and hypo- or anhidrosis is known as Ross syndrome .

Individual evidence

  1. Otto Braun-Falco , Gerd Plewig , Helmut H. Wolff: Dermatology and Venerology. 5th edition. Springer, Berlin et al. 2005, ISBN 3-540-40525-9 , p. 915.