Allelic Disease

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With Allelic disorders are in the genetics various diseases referred to by different mutations on the same gene caused. It is based on various forms of expression ( alleles ) of the respective gene. Often these allele variants do not lead to the clinical picture of different diseases, but present themselves as a single disease, as a monogenic disease , one then speaks of 'allelic heterogeneity'.

Allelopathy , a branch of chemical ecology, should not be confused

Examples of allelic diseases are myotilinopathies and achondroplasia / hypochondroplasia .

Individual evidence

  1. entry to allelic disease in Flexikon , a wiki company DocCheck
  2. Ch. P. Schaar, J. Zschocke: "Basiswissen Humangenetik", Springer-Verlag, 2nd edition, 2013, eBook- ISBN 978-3-642-28907-1

Web links