Andreas Hierlemann

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Andreas Hierlemann (born August 17, 1964 in Ochsenhausen ) is a German chemist and professor of biosystems engineering at the ETH Zurich , Switzerland. He is known for his work in the field of CMOS -based chemical and biomicrosensor systems as well as high-density microelectrode arrays .

Life

From 1985 to 1991 Hierlemann studied chemistry at the University of Tübingen , Germany. He received there in 1996. his doctorate (PhD) for his work on mass sensitive detection of volatile organic compounds with modified polysiloxane . From 1997 to 1998 he worked as a postdoc at Texas A&M University in College Station , Texas, USA and at Sandia National Laboratories in Albuquerque, New Mexico, USA. From 1999 to 2004 he was research team leader at the Physical Electronics Laboratory at the Department of Physics at ETH Zurich, Switzerland, and in 2004 he became associate professor for microsensors. In 2008 Hierlemann became full professor for Biosystems Engineering at the Department for Biosystems Science and Engineering at ETH Zurich in Basel, Switzerland.

Scientific contribution

HIerlemann's research focus was initially on chemical sensors and microsensors. He worked in particular on the detection of volatile organic substances and on enantiomer detection in the gas phase. In addition, he dealt with microtechnology and specifically with the development of complex CMOS-based microsensor systems. His current interdisciplinary research is in the field of engineering and physics for applications in biology and medicine. This includes the development of CMOS-based, integrated chemical and biomicrosystems as well as the development of bioelectronic chips and high-density microelectrode arrays . High-density microelectrode arrays are used for basic research in the field of information processing by neurons or brain cells. In addition, Hierlemann's research group is working on the development of microfluidic chips in order to investigate the properties of single cells and micro-tissues.

Applications of the technologies that Hierlemann and his group are developing are in the fields of systems biology , pharmaceutical screening, personalized medicine and neurosciences .

Awards

  • 2005 IEEE Donald G. Fink Prize Paper Award
  • 2008 Eurosensors Fellow
  • 2011 DECHEMA Prize from the Max Buchner Research Foundation

Web links

Individual evidence

  1. ↑ a b c C. Hagleitner, A. Hierlemann, D. Lange, A. Kummer, N. Kerness, O. Brand, H. Baltes: Smart Single-Chip Gas Sensor Microsystem. In: Nature . Volume 414, 2001, pp. 293-296, doi: 10.1038 / 35104535 .
  2. ^ A. Hierlemann, R. Gutierrez-Osuna: Higher-order Chemical Sensing. In: Chemical Reviews . Volume 108, 2008, pp. 563-613, doi: 10.1021 / cr068116m .
  3. ↑ K. Bodenhöfer, A. Hierlemann, J. Seemann, G. Gauglitz, B. Koppenhoefer, W. Göpel: Chiral Discrimination using Piezoelectric and Optical Gas Sensors. In: Nature. Volume 387, 1997, pp. 577-580, doi: 10.1038 / 42426 .
  4. ↑ P. Kurzawski, A. Bogdanski, V. Schurig, R. Wimmer, A. Hierlemann: Opposite signs of capacitive microsensor signals upon exposure to the enantiomers of methyl propionates. In: Angewandte Chemie International Edition . Volume 47, 2008, pp. 913-916, doi: 10.1002 / anie.200704346 .
  5. ↑ a b A. Hierlemann: Integrated Chemical Microsensor Systems in CMOS Technology. Springer Verlag, 2005, ISBN 3-540-23782-8 , p. 229.
  6. ↑ a b S. Hafizovic, D. Barrettino, T. Volden, J. Sedivy, K.-U. Kirstein, O. Brand, A. Hierlemann: Single-chip mechatronic microsystem for surface imaging and force response studies. In: Proceedings of the National Academy of Sciences . Volume 101, No. 49, 2004, pp. 17011-17015.
  7. ↑ a b U. Frey, U. Egert, F. Heer, S. Hafizovic and A. Hierlemann: Microelectronic System for High-Resolution Mapping of Extracellular Electric Fields Applied to Brain Slices. In: Biosensors & Bioelectronics . Volume 24, 2009, pp. 2191-2198, doi: 10.1016 / j.bios.2008.11.028 .
  8. ↑ a b A. Hierlemann, U. Frey, S. Hafizovic, F. Heer: Growing Cells atop Microelectronic Chips: Interfacing Electrogenic Cells in Vitro with CMOS-based Microelectrode Arrays. In: Proceedings of the IEEE. Tape. 99, No. 2, 2011, pp. 252-284.
  9. ↑ a b D. J. Bakkum, U. Frey, M. Radivojevic, TL Russell, J. Müller, M. Fiscella, H. Takahashi, A. Hierlemann: Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites. In: Nature Communications. Volume 4, 2013, p. 2181, doi: 10.1038 / ncomms3181 .
  10. ^ IEEE Donald G. Fink Prize Paper Award Recipients
  11. ↑ Eurosensors fellows.
  12. ↑ When brain cells communicate with microchips - DECHEMA Prize 2011 for Andreas Hierlemann, ETH Zurich. DECHEMA , November 17, 2011, accessed on March 11, 2017 .
personal data
SURNAME Hierlemann, Andreas
BRIEF DESCRIPTION German chemist
DATE OF BIRTH 17th August 1964
PLACE OF BIRTH Ochsenhausen