CCL1
CCL1 | ||
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other names |
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Properties of human protein | ||
Mass / length primary structure | 96 amino acids, 10992 Da | |
Identifier | ||
Gene names | CCL1 P500; SISe; TCA3; I-309; SCYA1 | |
External IDs | ||
Orthologue | ||
human | House mouse | |
Entrez | 6346 | 20290 |
Ensemble | ENSG00000108702 | ENSMUSG00000020702 |
UniProt | P22362 | P10146 |
Refseq (mRNA) | NM_002981 | NM_011329 |
Refseq (protein) | NP_002972 | NP_035459 |
Gene locus | Chr 17: 34.36 - 34.36 Mb | Chr 11: 82.18 - 82.18 Mb |
PubMed search | 6346 |
20290
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CCL1 ( English CC-chemokine ligand 1 ) is a cytokine belonging to the family of the C-C chemokines .
properties
CCL1 is involved in inflammatory processes. It binds to CCR8 and is chemotactic for various immune cells , including monocytes , NK cells , immature B cells, and dendritic cells .
Individual evidence
- ^ Miller MD, Krangel MS: The human cytokine I-309 is a monocyte chemoattractant . In: Proc. Natl. Acad. Sci. USA . 89, No. 7, April 1992, pp. 2950-4. doi : 10.1073 / pnas.89.7.2950 . PMID 1557400 . PMC 48781 (free full text).
- ↑ Roos RS, Loetscher M, Legler DF, Clark-Lewis I, Baggiolini M, Moser B: Identification of CCR8, the receptor for the human CC chemokine I-309 . In: J. Biol. Chem. . 272, No. 28, July 1997, pp. 17251-4. doi : 10.1074 / jbc.272.28.17251 . PMID 9211859 .