CCL28

CCL28
other names	Chemokine (CC Motif) ligand 28 Mucosae-Associated Epithelial Chemokines Small Inducible Cytokine A28 SCYA28 MEC Chemokine (CC Motif) Ligand 28 Splice Variant Chi CCK1 protein
Properties of human protein
Mass / length primary structure	127 amino acids, 14280 Da
Identifier
External IDs	GeneCards :  CCL28 OMIM :  605240 UniProt :  Q9NRJ3
Orthologue
	human	House mouse
Entrez	56477	56838
UniProt	Q9NRJ3	Q9JIL2
PubMed search	56477	56838

CCL28 ( English CC chemokine ligand 28 ) is a cytokine belonging to the family of the C-C chemokines .

properties

CCL28 is involved in inflammatory processes. It binds to CCR3 on eosinophils and to CCR10 on T cells and B cells . CCL28 is produced in the intestines , lungs , mammary glands and salivary glands .

Individual evidence

1. ↑ Rodriguez et al. 2004. Differential gene expression by integrin 7+ and 7– memory T helper cells. BMC Immunol. 5: 13.
2. ↑ Kunkel et al. 2003. CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. J. Clin. Invest. 111: 1001-1010.
3. ↑ John et al. 2005, Temporal production of CCL28 corresponds to eosinophil accumulation and airway hyperreactivity in allergic airway inflammation, Am. J. Pathol. 166: 345-353.