CD2

T-cell surface antigen CD2
	according to PDB 1CDB
other names	Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11 / Leu-5
	Existing structural data : PDB 1GYA , PDB 1HNF
Properties of human protein
Mass / length primary structure	351 amino acids , 39,448 Da
Identifier
External IDs	GeneCards : CD2 ; UniProt : P06729 ;

T-cell surface antigen CD2 is a surface protein .

properties

CD2 binds to LFA-3 (CD58) and CD48 / BCM1 and mediates cell adhesion between T cells and other cell types. CD2 is involved in the activation of T cells. The cytoplasmic area transmits signal transduction , which leads to an increase in the secretion of interferon-gamma and interleukin 8 and the formation of tumor necrosis factor . CD2 is glycosylated and has disulfide bridges .