Early Activation Antigen CD69

Early activation antigen CD69
according to PDB  1E87
other names	Activation inducer molecule, AIM
Existing structure data : PDB  1E8I , PDB  1FM5
Properties of human protein
Mass / length primary structure	199 amino acids , 22,559 Da
Identifier
External IDs	GeneCards :  CD69 OMIM :  107273 UniProt :  Q07108
Orthologue (human)
Entrez	969
Ensemble	ENSG00000110848
UniProt	Q07108
Refseq (mRNA)	NM_001781.2
Refseq (protein)	NP_001772.1
PubMed search	969

Early activation antigen CD69 is a surface protein from the group of cell adhesion molecules .

properties

CD69 is produced by activated T cells , B cells , NK cells , neutrophils , eosinophils , Langerhans cells and platelets . It acts as an immunomodulator after activation. CD69 binds divalent calcium ions and is glycosylated and phosphorylated .

Web links

• MeSH Early Activation Antigen CD69

Individual evidence

1. ↑ D. Sancho, M. Gómez, F. Sánchez-Madrid: CD69 is an immunoregulatory molecule induced following activation. In: Trends in immunology. Volume 26, Number 3, March 2005, pp. 136-140, doi : 10.1016 / j.it.2004.12.006 , PMID 15745855 .