CD87

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Urokinase plasminogen activator surface receptor
Urokinase plasminogen activator surface receptor
according to PDB  1YWH
other names

Monocyte activation antigen Mo3, CD87

Existing structure data : PDB  2FD6 , PDB  2I9B

Properties of human protein
Mass / length primary structure 335 amino acids , 36,978 Da
Identifier
External IDs
Orthologue (human)
Entrez 5329
Ensemble ENSG00000011422
UniProt Q03405
Refseq (mRNA) NM_001005376.2
Refseq (protein) NP_001005376.1
PubMed search 5329

CD87 (synonym urokinase plasminogen activator surface receptor , urokinase receptor for short ) is a surface protein .

properties

CD87 is formed by neurons in the area of ​​the central sulcus . It is the receptor of the urokinase plasminogen activator and promotes the formation of plasmin . CD87 is glycosylated and has a GPI anchor . In addition to the plasminogen activator, vitronectin and high-molecular kininogen bind .

Web links

Individual evidence

  1. G. Zhang, AA Eddy: Urokinase and its receptors in chronic kidney disease. In: Frontiers in bioscience: a journal and virtual library. Volume 13, May 2008, pp. 5462-5478, PMID 18508599 , PMC 3142275 (free full text).