CXCL14
CXC motif chemokine 14 | ||
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other names |
Chemokine BRAK, MIP-2G, Small-inducible cytokine B14 |
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Properties of human protein | ||
Mass / length primary structure | 111 amino acids , 13,078 Da | |
Identifier | ||
External IDs | ||
Orthologue (human) | ||
Entrez | 9547 | |
Ensemble | ENSG00000145824 | |
UniProt | O95715 | |
Refseq (mRNA) | NM_004887.4 | |
Refseq (protein) | NP_004878.2 | |
PubMed search |
9547
|
CXC motif chemokine 14 is a protein belonging to the chemokine group . As a chemokine, it is a surface protein and is involved in the immune response . The chemokine serves as a cellular warning signal. Immune cells with a suitable chemokine receptor bind to the chemokine , as a result of which immune cells accumulate at the site of inflammation and the immune response is strengthened locally. As a CXC chemokine, it has four cysteines , the first two of which have any amino acid X in between, followed by 24 amino acids up to the third cysteine and 15 amino acids between the third and fourth cysteines.
literature
- Kenneth Murphy: Janeway's Immunobiology, 9th edition. Garland Science, 2016, ISBN 978-1-315-53324-7 , pp. 453-456. The 5th English edition is available online on the pages of the NCBI Bookshelf (online) .
- Zlatko Dembic: The Cytokines of the Immune System. Academic Press, 2015, ISBN 978-0-124-20010-4 . Pp. 255-258.
- Frans P. Nijkamp: Principles of Immunopharmacology. Springer Science & Business Media, 2011, ISBN 978-3-034-60136-8 , pp. 72-74.
- Dieter Adam: Infectiology. Springer-Verlag, 2013, ISBN 978-3-642-18577-9 , pp. 32–33.
Web links
Individual evidence
- ↑ Werner Luttmann: The Experimenter: Immunology. Springer-Verlag, 2014, ISBN 978-3-642-41899-0 , pp. 278-280.
- ^ Robert R. Rich: Clinical Immunology. Elsevier Health Sciences, 2012, ISBN 978-0-723-43710-9 , pp. 136-140.