CXCL7
| Platelet basic protein | ||
|---|---|---|
| other names |
CXC motif chemokine 7, leukocyte-derived growth factor, LDGF |
|
| Properties of human protein | ||
| Mass / length primary structure | 128 amino acids , 13,894 Da | |
| Identifier | ||
| External IDs | ||
| Orthologue (human) | ||
| Entrez | 5473 | |
| Ensemble | ENSG00000163736 | |
| UniProt | P02775 | |
| Refseq (mRNA) | NM_002704.3 | |
| Refseq (protein) | NP_002695.1 | |
| PubMed search |
5473
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Platelet basic protein (synonym CXCL7 ) is a protein from the group of chemokines . As a chemokine, it is a surface protein and is involved in the immune response . The chemokine serves as a cellular warning signal. Immune cells with a suitable chemokine receptor bind to the chemokine , as a result of which immune cells accumulate at the site of inflammation and the immune response is strengthened locally. As a CXC chemokine, it has four cysteines , the first two of which have any amino acid X in between, followed by 24 amino acids up to the third cysteine and 15 amino acids between the third and fourth cysteines.
literature
- Kenneth Murphy: Janeway's Immunobiology, 9th edition. Garland Science, 2016, ISBN 978-1-315-53324-7 , pp. 453-456. The 5th English edition is available online on the pages of the NCBI Bookshelf (online) .
- Zlatko Dembic: The Cytokines of the Immune System. Academic Press, 2015, ISBN 978-0-124-20010-4 , pp. 255-258.
- Frans P. Nijkamp: Principles of Immunopharmacology. Springer Science & Business Media, 2011, ISBN 978-3-034-60136-8 , pp. 72-74.
- Dieter Adam: Infectiology. Springer-Verlag, 2013, ISBN 978-3-642-18577-9 , pp. 32–33.
Web links
Individual evidence
- ↑ Werner Luttmann: The Experimenter: Immunology. Springer-Verlag, 2014, ISBN 978-3-642-41899-0 , pp. 278-280.
- ^ Robert R. Rich: Clinical Immunology. Elsevier Health Sciences, 2012, ISBN 978-0-723-43710-9 , pp. 136-140.