Byssinosis

Classification according to ICD-10
J66.0	Byssinosis Respiratory disease from cotton dust
J66.1	Flax worker disease
J66.2	Cannabiosis
ICD-10 online (WHO version 2019)

When byssinosis (including hemp workers lung, cotton fever , Monday fever , Weber cough . Or English farmer's lung ) is, a disease of the lungs due to inhalation of cotton - hemp or flat dusts . The disease is recognized in Germany as an occupational disease (BK4202).

properties

In the case of chronic exposure, workers who work in the production of bast fibers and textiles made from raw cotton , raw flax or raw hemp (e.g. panting the raw fibers) are particularly at risk .

Due to the glycosidic bond of the type β1 → 4, natural cellulose- based fibers and their dusts can not be broken down by mammals , as they lack the cellulases required for this . Dusts less than ten micrometers in diameter are alveolar . Depending on the cleaning process, there are also different amounts of remaining plant and bacterial antigens from the starting material, which can generate an immune reaction . Frequent inhalation of the dusts from cellulose-based natural fibers can lead to bioaccumulation in the lungs. The contribution of both causes to the development of byssinosis is not yet fully understood.

Symptoms of byssinosis are shortness of breath, coughing and occasionally sputum and non-specific general symptoms, typically as part of Monday symptoms. The disease is divided into three stages, with stage III causing partially irreversible secondary changes to the lungs (centrilobular emphysema ) and heart . The course is similar to that of COPD .

Literary reception

In the 1854 novel North and South by Elizabeth Gaskell , the character Bessy Higgins dies of byssinosis.

literature

• Carina Steyer: Byssinosis. Occupational disease of the hemp workers. 6/2016, pharmaceuticalische-zeitung.de From the first hemp harvest in 1996 in Germany

Web links

• Leaflet for BK4202 . Retrieved March 25, 2012.
• MEDLINE database, keyword byssinosis . Retrieved April 5, 2013.

Individual evidence

1. ↑ ^{a b c} N. Konietzko, H. Wendel, B. Wiesner: Diseases of the lungs. Walter de Gruyter 1994, ISBN 3-11-012130-1 , p. 220f.
2. ^ AG Hollander: Byssinosis. In: Dis Chest. (1953), Vol. 24 (6), pp. 674-678. PMID 13107566 .
3. ↑ Jeremy M. Berg, John L. Tymoczko, Lubert Stryer: Stryer Biochemistry. 7th edition. Springer-Verlag, Berlin / Heidelberg 2013, ISBN 978-3-8274-2988-9 , p. 331.
4. ↑ V. Castranova, DG Frazer, LK Manley, RD Dey: Pulmonary alterations associated with inhalation of occupational and environmental irritants. In: Int Immunopharmacol . (2002), Vol. 2 (2-3), pp. 163-172. PMID 11811921 .
5. Jump up ↑ E. Tátrai, M. Brozik, Z. Adamis, K. Merétey, G. Ungváry: In vivo pulmonary toxicity of cellulose in rats. In: J Appl Toxicol. (1996), Vol. 16 (2), pp. 129-135. PMID 8935786 .
6. ↑ L. Rushton: Occupational causes of chronic obstructive pulmonary disease. In: Rev Environ Health. (2007), Volume 22 (3), pp. 195-212. PMID 18078004 .
7. ↑ DC Christiani, XR Wang: Respiratory effects of long-term exposure to cotton dust. In: Curr Opin Pulm Med. (2003), Volume 9 (2), pp. 151-155. PMID 12574696 .
8. ^ Pschyrembel Online. Retrieved February 2, 2019 . 

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !