Chastek paralysis

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The Chastek paralysis is a vitamin B 1 -Mangelerkrankung for fur animals (especially farm minks and - foxes ). It is triggered by feeding raw fish and its intestines, which contain large amounts of thiaminases and thus break down vitamin B 1 . It therefore largely corresponds to the thiamine deficiency encephalopathy in cats . Chastek is the name of the owner of the fox farm in Glencoe (Minnesota) , USA, where the disease was first observed in 1932 by feeding raw carp .

Clinically, the disease manifests itself through uncoordinated movements, unsteady gait with a hunched back, paralysis of all four limbs, opisthotonus and later convulsions .

Pathologically and anatomically, bilateral symmetrical astrocytic edema can be seen in various core areas , especially in the lateral knee cusps and the quadrilateral plateau , but also in the thalamus , midbrain and hindbrain and in the cerebral cortex . In addition, there is necrosis of the nerve cells and bleeding .

literature

  • Erwin Dahme, Eugen Weiss: Outline of the special pathological anatomy of domestic animals . 6th edition. Georg Thieme, Stuttgart 2007, ISBN 978-3-8304-1100-0 , p. 287 .

Individual evidence

  1. ^ The Conservation Volunteer. Volumes 3-4, Minnesota. Dept. of Conservation, 1941, p. 16.