Disposition prophylaxis
The disposition Prophylaxis in including infectious diseases all measures that individual susceptibility to infectious disease decrease. One speaks here of a reduction in the individual susceptibility to illness. In contrast to exposure prophylaxis , disposition prophylaxis does not aim at avoiding contact with pathogens, but at the outbreak of a disease in an individual or a less severe course of the disease after infection. Disposition prophylaxis is part of infection protection .
The susceptibility of an individual can be temporarily reduced by taking preventive anti-infectives . Examples include the preventive intake of antibiotics in the event of bacterial infectious diseases by contact persons ( rifampicin in meningococcal meningitis ) or antivirals in viral infections ( neuraminidase inhibitors in influenza ).
The measures for disposition prophylaxis, which are significant in terms of scope, are active and passive vaccinations . This can be both a preventive, hazard-dependent disposition prophylaxis and after excitation contact as post-exposure prophylaxis , before exciter contact as pre-exposure prophylaxis are performed.
Disposition prophylaxis also includes all measures to increase the individual's defense against infection, such as improving the nutritional status and avoiding immunosuppressive influences such as B. Toxins and measures such as immunosuppressive therapies (where these can be avoided). Particularly in the fight against tuberculosis , when specific, antibacterial therapies were not yet available, "disposition prophylaxis in the sense of a natural healthy lifestyle" was a decisive measure to reduce the incidence of tuberculosis.
literature
- N. Suttorp, M. Mielke, W. Kiehl, B. Piece (editor): Infectious diseases . Stuttgart 2004 ISBN 313-131691-8 p. 6 f
Individual evidence
- ^ Franz Hamburger: The tuberculosis of childhood . Leipzig 1912 p. 215