Edward Calabrese

from Wikipedia, the free encyclopedia

Edward J. Calabrese (* 1946 ) is an American toxicologist and professor at the University of Massachusetts Amherst (School of Public Health and Health Science).

Calabrese grew up in Bridgewater (Massachusetts) and studied at Bridgewater State College with a bachelor's degree in 1968 and at the University of Massachusetts Amherst with a master's degree in 1972 and a Ph.D. in 1973. He later became a professor there and is the director of the Northeast Regional Environmental Public Health Center at the University of Massachusetts.

He has dealt with carcinogens, risk assessment and mutual interactions of chemical substances in the environment and with the effects of low doses of drugs, environmental substances and radiation ( dose-response curve at low doses) and is known and controversial as a proponent of the old Paracelsian concept of hormesis . In his opinion, this also applies to ionizing radiation.

In 2011 he also criticized the LNT model of the linear extrapolation of the effects of ionizing radiation without a threshold value and accused its founders, Hermann Muller and Curt Stern, of deliberate misinterpretation of their experiments, which sparked heated controversy.

He wrote several books and around 750 scientific publications (2017).

He is on the Advisory Committee of the National Academy of Sciences and NATO on Clean Drinking Water, the Scientific Advisory Board of the Agency for Toxic Substances and Disease Registry (ATSDR), and chairs the Committee on Biological Effects of Low Level Exposures (BELLE).

He is the editor of Dose-Response .

In 2013 he received an honorary doctorate from McMaster University. In 2009 he received the Curie Prize from the World Council of Nuclear Workers.

Fonts

  • Principles of Animal Extrapolation, Wiley 1983
  • Nutrition and Environmental Health, 2 volumes, Wiley 1980, 1981
  • Ecogenetics: genetic variation in susceptibility to environmental agents, Wiley 1984
  • Toxic susceptibility: male / female differences, Wiley 1985
  • Multiple Chemical Interaction, Chelsea: Lewis 1991
  • with Elaina Kenyon: Air Toxics and Risk Assessment, Chelsea (Michigan): Lewis 1991
  • Published in: Biological Effects of Low Level Exposures to Chemical and Radiation, CRC Press 2017
  • Hormesis: a revolution in toxicology, risk assessment and medicine, EMBO Reports, Volume 5, Suppl. 1, 2004, pp. S37 – S40, PMC 1299203 (free full text)
  • Hormesis: a fundamental concept in biology, Microbial Cell, Volume 1, Issue 5, 2014, pp. 145–149, PMC 5354598 (free full text)
  • with Mark Mattson (Ed.): Hormesis: A Revolution in Biology, Toxicology and Medicine, Springer 2010
  • Muller's Nobel Prize Lecture: when ideology prevailed over science, Toxicol. Sci., Vol. 126, 2012, pp. 1-4, PMID 22166484

Web link

Individual evidence

  1. ↑ Marcel Krok, Attack on radiation geneticists triggers furor , Science Magazine, October 18, 2011
  2. ↑ Press release Curie Prize University of Massachusetts 2009
personal data
SURNAME Calabrese, Edward
ALTERNATIVE NAMES Calabrese, Edward J.
BRIEF DESCRIPTION American toxicologist
DATE OF BIRTH 1946