Endothelial selectin

E-selectin
according to PDB  1ESL
other names	CD62 antigen-like family member E, endothelial leukocyte adhesion molecule 1, ELAM-1
Existing structure data : PDB  1G1T , PDB  1KJA
Properties of human protein
Mass / length primary structure	610 amino acids , 66,655 Da
Identifier
External IDs	GeneCards :  SELE OMIM :  131210 UniProt :  P16581
Orthologue (human)
Entrez	6401
Ensemble	ENSG00000007908
UniProt	P16581
Refseq (mRNA)	NM_000450.2
Refseq (protein)	NP_000441.2
PubMed search	6401

E-selectin (synonym E-selectin , CD62E ) is a surface protein from the group of selectins .

properties

E-selectin is a lectin and participates in cell adhesion in an immune reaction . It mediates cell contacts between neutrophils and endothelial cells by binding to PSGL1 . E-selectin is glycosylated .

Web links

• MeSH endothelial selectin

Individual evidence

1. ^ T. Collins, A. Williams, GI Johnston, J. Kim, R. Eddy, T. Shows, MA Gimbrone, MP Bevilacqua: Structure and chromosomal location of the gene for endothelial-leukocyte adhesion molecule 1. In: The Journal of biological chemistry. Volume 266, Number 4, February 1991, pp. 2466-2473, PMID 1703529 .