Eucarbon
Eucarbon is the trade name of a finished medicinal product that was developed in Austria in 1909. It is a combination of plant and mineral ingredients and is traditionally used as a mild laxative ( laxative used) against mild forms of constipation.
Origin of name and dosage form
The name Eucarbon is etymologically derived from the Greek εὐ 'good' and carbon ( carbon ). The dosage form are uncoated, black-gray tablets without a break line.
history
In 1909 F. Trenka and Wolfgang Josef Pauli (father of Nobel Prize winner and physicist Wolfgang Ernst Pauli ) developed Eucarbon in a Viennese pharmacy. As a result, production was set up in Vienna. In 1914 the export to Germany, Hungary and Italy began. Licenses were acquired for Mexico and Turkey. In 1929 there was a partnership and the entry of F. Trenka in the commercial register. In 1948 exports were expanded to the Arab region as well as to Saudi Arabia, Libya, Syria, Lebanon, Jordan, etc. In 1978, Heinz-Georg Kamler and Michaela Kamler took over the Trenka company and introduced more modern production methods in accordance with WHO ( Good Manufacturing Practice ) standards . The blister pack has existed since 1992. Eucarbon was exported to around 40 countries in the 1990s. In 2002, Eucarbon was launched in Romania, Estonia, Ukraine and other countries. In 2015 Eucarbon will be distributed in more than 70 countries worldwide. Since the company was founded in 1909 until 2015, around 8.2 billion tablets were sold worldwide.
pharmacology
Active ingredients and mechanism of action
The active ingredients of Eucarbon are medicinal charcoal, rhubarb root extract , senna leaves and sulfur. Medicinal charcoal is supposed to act as an adsorbent, whereby the senna leaves that are present at the same time are supposed to ensure that the toxic substances bound to the charcoal are quickly eliminated. Senna leaves contain antraquinone glycosides , which stimulate the peristalsis of the intestine. They work in the large intestine and reduce the absorption of fluids and salts there. Due to the lower water absorption, the stool remains soft and bowel movements are made easier. Other ingredients are essential oils from mint and fennel . The laxative ( laxative ) effect is about 8-10 hours after ingestion. Depending on the dosage, Eucarbon has a slightly laxative or constipating effect and thus regulates slight digestive malfunctions.
Side effects and contraindications
Occasional abdominal pain and diarrhea were observed, especially when the doses were too high. Very rarely (less than 1 in 10,000 people) may feel sick or be sick. Allergic reactions can rarely occur. As with other laxatives, long-term use of high doses can lead to a loss of minerals, particularly potassium, which can make intestinal sluggishness worse. This can manifest itself in muscle weakness and constipation caused by restricted bowel movement. A faint red coloration of the urine is insignificant and can occasionally be observed in its alkaline reaction.
Web links
Anniversary 100 years Eucarbon (Apotheker Krone 23/09)
Individual evidence
- ↑ Eucarbon.com history ( page no longer available , search in web archives ) Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice.
- ↑ Eucarbon worldwide ( page no longer available , search in web archives ) Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice.
- ↑ a b Technical information Eucarbon tablets , F. TRENKA Chem.-Pharmaceutical Factory Ges.mbH, as of September 2014.
