Fcγ receptors

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Fcγ receptors are a group of surface proteins from the group of Fc receptors . Fcγ receptors bind immunoglobulin G , depending on the subtype and receptor with different affinity . They are involved in the immune response by activating phagocytes to phagocytosis . Examples of Fcγ receptors are Fcγ receptor Ia , Fcγ receptor Ib and Fcγ receptor Ic , which are referred to as CD64a , CD64b and CD64c . Further examples are Fcγ receptor IIa (synonym CD32a), Fcγ receptor IIb (synonym CD32b), Fcγ receptor IIc , Fcγ receptor IIIa (synonym CD16a) and Fcγ receptor IIIb (synonym CD16b).

Individual evidence

  1. ↑ QM Hanson, AW Barb: A perspective on the structure and receptor binding properties of immunoglobulin G Fc. In: Biochemistry. Volume 54, number 19, May 2015, pp. 2931-2942, doi: 10.1021 / acs.biochem.5b00299 , PMID 25926001 , PMC 4894528 (free full text).
  2. ^ J. Lu, PD Sun: Structural mechanism of high affinity FcγRI recognition of immunoglobulin G. In: Immunological reviews. Volume 268, Number 1, November 2015, pp. 192-200, doi: 10.1111 / imr.12346 , PMID 26497521 .