Gasperini Syndrome

Classification according to ICD-10
G46.3	Brain stem syndrome
ICD-10 online (WHO version 2019)

The Gasperini's syndrome is a very rare brain stem syndrome (alternating Pons - Syndrome ) due to a lesion caudal the bridge hood with the main features of an ipsilateral paralysis of the III. to XII. Cranial nerve and contralateral sensitivity disorder .

In the current medical literature, the term is used for the combination of ipsilateral (equilateral) lesion of the 5th to 7th cranial nerve with contralateral (on the opposite side) unilateral hypoesthesia .

The term bridge hood syndrome is used synonymously .

The name refers to the author of the first description from 1912 by the Italian doctor Ubaldo Gasperini .

Clinical manifestations

The clinic is based on the existing nerve deficits, s. V. trigeminal nerve (triple nerve ), VI. · Abducens (Augenabziehnerv) and VII. Facial nerve (facial nerve).

The cause is usually a heart attack or bleeding in the pons.

literature

M. Krasnianski, T. Müller, S. Zierz, M. Winterholler: Gasperini syndrome as clinical manifestation of pontine demyelination. In: European journal of medical research. Vol. 14, No. 9, September 2009, pp. 413-414, PMID 19748860 , PMC 3351973 (free full text).
M. Schwaninger, K. Kanemoto, HW Kölmel: The Gasperini syndrome - a differential diagnosis of peripheral facial paralysis. Neurological and imaging findings. In: ENT. Vol. 41, No. 11, November 1993, pp. 536-538, PMID 8282579 .

Individual evidence

↑ P. Tacik, A. Alfieri, M. Kornhuber, D. Dressler: Gasperini's syndrome: its neuroanatomical basis now and then. In: Journal of the history of the neurosciences. Vol. 21, No. 1, January 2012, pp. 17-30, doi: 10.1080 / 0964704X.2011.568045 , PMID 22239093 .
↑ ^a ^b M. Krasnianski, T. Müller, S. Zierz, M. Winterholler: Gasperini syndrome as clinical manifestation of pontine demyelination. In: European journal of medical research. Vol. 14, No. 9, 2009 pp. 413-414, doi : 10.1186 / 2047-783X-14-9-413 . PMC 3351973 (free full text).
^ U. Gasperini: Di un caso di emorragia protuberenziale. Contributo clinico allo studio delle sindromi pontine inferiori. In: Rif Med . 1912, Vol. 28 pp. 880-883, 898-905.

[1] P. Tacik, A. Alfieri, M. Kornhuber, D. Dressler: Gasperini's syndrome: its neuroanatomical basis now and then. In: Journal of the history of the neurosciences. Vol. 21, No. 1, January 2012, pp. 17-30, doi: 10.1080 / 0964704X.2011.568045 , PMID 22239093 .

[Kras-2] M. Krasnianski, T. Müller, S. Zierz, M. Winterholler: Gasperini syndrome as clinical manifestation of pontine demyelination. In: European journal of medical research. Vol. 14, No. 9, 2009 pp. 413-414, doi : 10.1186 / 2047-783X-14-9-413 . PMC 3351973 (free full text).

[3] U. Gasperini: Di un caso di emorragia protuberenziale. Contributo clinico allo studio delle sindromi pontine inferiori. In: Rif Med . 1912, Vol. 28 pp. 880-883, 898-905.