Hemorrhagic Diathesis

Classification according to ICD-10
D65-D69	Coagulopathies, purpura and other hemorrhagic diatheses
ICD-10 online (WHO version 2019)

A hemorrhagic diathesis is understood to mean a pathologically increased tendency to bleeding (" bleeding disease"). It is a specific form of diathesis . Symptoms of hemorrhagic diathesis can be any abnormal bleeding such as: B. a prolonged bleeding time (> 6 min.), Bruises ( hematomas ) without force or after minor injuries, bleeding gums and bleeding in the digestive tract or in the joints .

Above all, diseases associated with an increased tendency to bleed are

• Disorders of blood clotting ( coagulation ) (about 20%)
• Decrease in the number of blood platelets ( thrombopenia ) or disorders of the blood platelets ( thrombocytopathy ) (approx. 70%)
• Diseases of the blood vessels (vascular hemorrhagic diathesis) (approx. 10%), for example in:
  • scurvy
  • Purpura , Henoch-Schönlein purpura , protein C deficiency (purpura fulminans)
  • Osler's disease
• rarely poisoning with anticoagulants ( rat poisons from the group of coumarins , such as bromadiolone or difenacoum ).

There are also very rare syndromes with an increased tendency to bleeding, such as a hereditary combined deficiency of vitamin K-dependent coagulation factors .

literature

• S2k guideline thrombocytopathies of the Society for Thrombosis and Haemostasis Research (GTH). In: AWMF online (as of 2012)

See also

• Hemhidrosis
• Bovine neonatal pancytopenia ("blood sweating" of the calves)