Hans Konrad Biesalski

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Hans Konrad Biesalski (born April 14, 1949 in Marburg ) is a German nutritionist and professor of biological chemistry and nutritional science at the University of Hohenheim .

Life

Hans Konrad Biesalski studied medicine at the Universities of Mainz and Bonn. In 1979 he was licensed as a doctor. 1979–1982 Biesalski was an assistant at the Physiological Institute of the University of Mainz in the department of biophysics. He received his doctorate in 1981 and his habilitation in 1986. From 1984–93 he worked at the Institute for Physiological Chemistry at the University of Mainz, and in 1992 as a nutritionist (German Academy for Nutritional Medicine, DAEM). In 1993 he was appointed to the chair of biological chemistry and nutritional science at the University of Hohenheim; he still heads the institute today. He is the Managing Director of the University's Food Security Center. In 2007 he was appointed a Fellow at the Wissenschaftskolleg zu Berlin .

Act

Biesalski carried out work on the importance of vitamin A for the development and function of the inner ear as well as for lung function (maturation and mucosal barrier). In particular, the first-time description of the storage of vitamin A (retinyl ester) in organs and tissues outside of the liver were new findings for research into vitamin A metabolism. In 1995 he was able to prove that in addition to the classic route of distribution of the vitamin from the liver as retinol (vitamin A 1 ) bound to a retinol-binding protein (RBP), there is an alternative metabolic pathway via circulating retinyl esters , previously only known from carnivores : a pair of siblings with a mutation of the gene for RBP and consequently non-measurable blood levels of retinol showed, apart from minor skin changes and night blindness, no visible abnormalities that would be typical of a vitamin A deficiency. In fact, the two young girls had the carnivore route of distribution. Later, Biesalski dealt with questions of the recording and treatment of hidden hunger (micronutrient deficiency) and food security as well as questions of micronutrient deficits and their therapy (especially vitamin C) in intensive care patients. Another experimental field is nutritargeting, which he described in detail for the first time, that is, the development of galenic formulations that allow a targeted supply of nutrients to organs.

Biesalski’s most recent scientific work focuses on: a. Studies of the retinoid metabolism and studies on the importance of vitamins for human health. He leads or is involved in research projects of the Federal Ministry of Education and Research ( BMBF ) on the subject of world hunger and food quality. Biesalski is the editor of fourteen books and published 280 papers. In 2013 he published the book The Hidden Hunger .

Awards

  • 1982 HERMES Vitamin Prize
  • 1993 Fritz Wörwag Prize

2017 Research Prize of the Society for Vitamin Research 2017 Justus von Liebig Prize for World Food

Memberships

  • Until 2009 member of the expert group of the Global Food Security Board (WHO / FAO)
  • Until 2004 spokesman for the nutrition and cancer commission of the German Society for Hematological Oncology
  • Until 2010 member of the scientific advisory board of the US Pharmacopeia.
  • Editor Nutrition and Metabolism in Oncology; European Editor: Nutrition, Nutrition and Metabolism.

2015-2019 member of the scientific advisory board of the Federal Ministry of Food and Agriculture

Publications (books)

  • Hans Konrad Biesalski: Vitamins, trace elements and minerals: indication, diagnosis, therapy . 2nd Edition. Thieme, Stuttgart 2019, ISBN 978-3-13-242735-8 .
  • Hans Konrad Biesalski: Our nutritional biography. Those who know them live more healthily . 1st edition. Albrecht Knaus, Berlin 2017, ISBN 978-3-8135-0764-5 .
  • Hans Konrad Biesalski: The hidden hunger: being full is not enough . Springer Spectrum, 2013, ISBN 978-3-8274-2952-0 .
  • Hans Konrad Biesalski, Peter Grimm and Susanne Nowitzki-Grimm: Pocket Atlas Nutrition . 8th edition. Thieme, Stuttgart 2020, ISBN 978-3-13-242607-8 .
  • Hans Konrad Biesalski: Micronutrients as the engine of evolution . Springer Spectrum, 2015, ISBN 978-3-642-55396-7 .
  • Stephan C. Bischoff, Karoline Köchling and Hans Konrad Biesalski: Successful concept for the nutrition team in various medical institutions . 5th edition. Pabst Science Publishers, 2017, ISBN 978-3-13-100295-2 .
  • Hans K. Biesalski, Stephan C. Bischoff, Christoph Puchstein: Nutritional medicine: According to the nutritional medicine curriculum of the German Medical Association . 5th edition. Thieme, Stuttgart 2017, ISBN 978-3-13-100295-2 .
  • Wolfgang Hartig, Hans Konrad Biesalski Wilfred Druml, Peter Fürst, Arved Weimann: Nutritional and infusion therapy: standards for clinics, intensive care units and outpatient departments . 8th edition. Thieme, 2003.
  • Hans Konrad Biesalski: Vitamins, trace elements and minerals: indication, diagnosis, therapy . 2nd Edition. Thieme, 2019, ISBN 978-3-13-242735-8 .
  • HansKonrad Biesalski, Gudrun Zürcher, Karin Hofele: Eating healthily and consciously in cancer: How to use protective substances and strengthen your immune system. Eat with appetite and joy. Delicious recipes from the whole food kitchen . 2nd Edition. Trias, 2009, ISBN 978-3-8304-3004-9 .
  • Hans Konrad Biesalski: Vitamins: Building Blocks of Life . 1st edition. CH Beck, 1997, ISBN 978-3-406-41860-0 .
  • Hans-Konrad Biesalski Food that harms, food that heals: [the indispensable guide from A - Z] 1st edition 1997, Stuttgart / Zurich / Vienna

Web links

Individual evidence

  1. ↑ Biesalski HK, Wellner U, Weiser H. Vitamin A deficiency increases noise susceptibility in guinea pigs. J Nutr. 1990 Jul; 120 (7): 726-37
  2. ↑ Biesalski HK, Weiser H. Sensitive analysis of retinyl esters by isocratic adsorption chromatography. J Clin Chem Clin Biochem. 1989 Feb; 27 (2): 65-74
  3. ^ Biesalski HK. Aspects of vitamin A metabolism in sensory epithelia (inner ear, olfactory bulbus, pineal gland). Int J Vitam Nutr Res Suppl. 1985; 27: 225-45
  4. ↑ Biesalski HK, Nohr D New aspects in vitamin a metabolism: the role of retinyl esters as systemic and local sources for retinol in mucous epithelia. J Nutr. 2004 Dec; 134 (12 Suppl): 3453S-3457S
  5. ↑ Biesalski HK, Frank J, Beck SC, Heinrich F, Illek B, Reifen R, Gollnick H, Seeliger MW, Wissinger B, Zrenner E. Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol binding protein. At J Clin Nutr. 1999 May; 69 (5): 931-6. Erratum in: Am J Clin Nutr 2000 Apr; 71 (4): 1010
  6. ↑ Seeliger MW, Biesalski HK, Wissinger B, Gollnick H, Gielen S, Frank J, Beck S, Zrenner E. Phenotype in retinol deficiency due to a hereditary defect in retinol binding protein synthesis.Invest Ophthalmol Vis Sci. 1999
  7. ↑ Jati IR, Vadivel V, Nöhr D, Biesalski HK. Nutrient density score of typical Indonesian foods and dietary formulation using linear programming. Public Health Nutr. 2012 Dec; 15 (12): 2185-92
  8. ↑ Inayati DA, Scherbaum V, Purwestri RC, Wirawan NN, Suryantan J, Hartono S, Bloem MA, Pangaribuan RV, Biesalski HK, Hoffmann V, Bellows AC. Combined intensive nutrition education and micronutrient powder supplementation improved nutritional status of mildly wasted children on Nias Island, Indonesia. Asia Pac J Clin Nutr. 2012; 21 (3): 361-73
  9. ^ Biesalski HK. Parenteral ascorbic acid as a key for regulating microcirculation in critically ill. Crit Care Med. 2008 Aug; 36 (8): 2466-8
  10. ↑ Biesalski HK, Tinz J. Nutritargeting. Adv Food Nutr Res. 2008; 54: 179-217
personal data
SURNAME Biesalski, Hans Konrad
BRIEF DESCRIPTION German medic
DATE OF BIRTH April 14, 1949
PLACE OF BIRTH Marburg