Hiatus leucaemicus
The hiatus leucaemicus or leukemic gap is the general absence of mean stages of myelopoiesis maturation in the differential blood count or in the bone marrow . In the hiatus leucaemicus there are only very mature and very immature leukocytes (segmented granulocytes and blasts ). The intermediate stages ( promyelocytes , metamyelocytes , myelocytes , rod-like granulocytes) are largely absent ("hiatus"). The hiatus leucaemicus is typical of acute myeloid leukemia . In chronic myeloid leukemia , on the other hand, there is no hiatus leukaemicus , but the entire continuum of the various stages of maturation is found here, with the percentage of blasts usually being low.
Individual evidence
- ↑ H.-W. Baenkler among others: internal medicine. Georg Thieme Verlag, 2001, ISBN 3-13-128751-9 , pp. 1407-1408, (online)