Heat cancer

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As heat cancer is called skin or mucosa - cancers that are caused by years of exposure to heat.

Examples and pathogenesis

The best known cancer induced by chronic heat exposure is kangri cancer . This is a skin carcinoma observed in the Kashmir Valley, which is caused as a result of prolonged exposure to heat from a coal stove worn under clothing - the kangri . The effect of heat initially creates reticulated pigmentation on the skin, a so-called erythema ab igne or Buschke heat melanosis. If the erythema becomes chronic, it can develop into a squamous cell carcinoma (spinaloma) after many years . These tumors are highly aggressive.

The chronic use of hot water bottles on the stomach can also cause squamous cell carcinoma over many years and the intermediate stage erythema ab igne .

In Ireland until the 1960s there were cancers induced by the heat of peat ovens.

In an epidemiological study from Iran , a clear connection between the consumption of very hot tea (> 70 ° C) and the occurrence of esophageal cancer was found. The province of Golestan has one of the highest rates of esophageal cancer worldwide. One possible cause of the carcinogenic effect that has been discussed is the chronic irritation and inflammation of the mucosa of the esophagus. Other studies, for example from South America, come to similar results.

In the cases mentioned, the heat is just bearable. There are no burns. This is the main difference to burn scar cancer , which develops from burn scars.

therapy

Individual evidence

  1. ↑ MA Teli, NA Khan et al. a .: Recurrence pattern in squamous cell carcinoma of skin of lower extremities and abdominal wall (Kangri cancer) in Kashmir valley of Indian subcontinent: impact of various treatment modalities. In: Indian journal of dermatology. Volume 54, Number 4, 2009, pp. 342-346, ISSN  1998-3611 . doi : 10.4103 / 0019-5154.57610 . PMID 20101335 . PMC 2807710 (free full text).
  2. ^ I. Wani: Kangri cancer. In: Surgery . Volume 147, Number 4, April 2010, pp. 586-588, ISSN  1532-7361 . doi : 10.1016 / j.surg.2009.10.025 . PMID 19932909 .
  3. ^ Dangerous bedfellow - cancer from hot water bottle. In: Gynecol Tribune. Volume 1, Number 10, 2000, p. 8.
  4. ↑ CM Rudolph, HP Soyer u. a .: Squamous cell carcinoma in erythema ab igne. In: The dermatologist. Volume 51, 2000, pp. 260-263.
  5. ↑ F. Cross: On a turf (peat) fire cancer: malignant change superimposed on erythema ab igne. In: Proceedings of the Royal Society of Medicine. Volume 60, Number 12, December 1967, pp. 1307-1308, ISSN  0035-9157 . PMID 6066580 . PMC 1901466 (free full text).
  6. ^ Steaming hot tea linked to cancer. On BBC News on March 27, 2009
  7. ↑ a b F. Islami, A. Pourshams, D. Nasrollahzadeh, F. Kamangar, S. Fahimi, R. Shakeri, B. Abedi-Ardekani, S. Merat, H. Vahedi, S. Semnani, CC Abnet, P. Brennan, H. Møller, F. Saidi, SM Dawsey, R. Malekzadeh, P. Boffetta: Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: population based case-control study. In: BMJ (Clinical research ed.). Volume 338, 2009, p. B929, ISSN  1756-1833 . PMID 19325180 . PMC 3269898 (free full text). doi : 10.1136 / bmj.b929
  8. ↑ F. Islami, F. Kamangar et al. a .: Oesophageal cancer in Golestan Province, a high-incidence area in northern Iran - a review. In: European Journal of Cancer . Volume 45, Number 18, December 2009, pp. 3156-3165, ISSN  1879-0852 . doi : 10.1016 / j.ejca.2009.09.018 . PMID 19800783 . (Review).
  9. ↑ P. Ghadirian: Thermal irritation and esophageal cancer in northern Iran. In: Cancer. Volume 60, Number 8, October 1987, pp. 1909-1914, ISSN  0008-543X . PMID 3652017 .
  10. ^ X. Castellsagué, N. Muñoz, u. a .: Influence of mate drinking, hot beverages and diet on esophageal cancer risk in South America. In: International journal of cancer. Journal international du cancer. Volume 88, Number 4, November 2000, pp. 658-664, ISSN  0020-7136 . PMID 11058886 .
  11. ↑ F. Islami, P. Boffetta et al. a .: High-temperature beverages and foods and esophageal cancer risk - a systematic review. In: International journal of cancer. Journal international du cancer. Volume 125, Number 3, August 2009, pp. 491-524, ISSN  1097-0215 . doi : 10.1002 / ijc.24445 . PMID 19415743 . PMC 2773211 (free full text). (Review).
  12. ↑ K. Miller, R. Hunt et al. a .: Erythema ab igne. In: Dermatology online journal. Volume 17, number 10, 2011, p. 28, ISSN  1087-2108 . PMID 22031654 . (Review).