Scar cancer

from Wikipedia, the free encyclopedia
Arm of a patient with burn scar cancer that developed from a burn scar

As scar carcinoma , also Marjolin ulcer called a one resulting from chronic irritation out called malignant tumors ( malignancy ) of the skin ( skin cancer ). In the English-language specialist literature, the terms scar carcinoma or Marjolin's ulcer are used.

A special form of scar carcinoma, the lung carcinoma scars (engl. Lung cancer scar or pulmonary scar cancer ).

description

Scar cancers are rare. They arise on the basis of chronic irritation of the skin. These can be unstable scars , chronic fistulas and ulcers (ulcers). The burn scar carcinoma is the most common form of cancer scars.

The name Marjolin ulcer goes back to the French surgeon Jean-Nicolas Marjolin , who in 1828 in the first edition of the Dictionnaire de Medécine was the first to describe the "wart-like ulcer", but not the malignant transformation of the ulcer into carcinoma. The transformation was first described by the British surgeon Caesar Hawkins (1798-1884). The term Marjolin ulcer was coined in 1903 by John Chalmers DaCosta (1863-1933).

histology

The scar carcinomas are mostly squamous cell carcinomas (spinaliomas). Basaliomas are much rarer.

Incidence

The incidence of scar cancer is relatively low. It depends on the irritation of the skin. In chronic osteomyelitis , the incidence is 0.7 to 1.5%. In the case of lower leg ulcers ("open leg", leg ulcer ) in 0.8% and in the case of decubitus (bed ulcer) in 0.5%. In the case of burn scars, it is in the range of 1 to 2%.

treatment

Scar carcinomas are usually surgically removed by incision . This involves cutting into the surrounding healthy tissue with a safety margin of at least 20 mm. Squamous cell carcinomas in particular are highly aggressive, so that a radical resection that is as deep as possible is necessary. In cases in which a local incision is no longer possible, an amputation may be indicated , if this is feasible .

Individual evidence

  1. ↑ JN Marjolin: Ulcère. In: Dictionnaire de medecine 1828, p. 31.
  2. ↑ A. Sharma, RA Schwartz, KG Swan: Marjolin's warty ulcer. In: Journal of Surgical Oncology . Volume 103, Number 2, February 2011, pp. 193-195, ISSN  1096-9098 . doi : 10.1002 / jso.21783 . PMID 21259256 . (Review).
  3. ↑ JC da Costa: Carcinomatous changes in an area of ​​chronic ulceration or Marjolin's ulcer. In: Annals of Surgery . Volume 37, 1903, pp. 496-502.
  4. ↑ a b c d Hans Lippert : Wundatlas: Compendium of complex wound treatment. 3rd edition, Georg Thieme Verlag, 2012, ISBN 3-131-57473-9 , p. 68. Restricted preview in the Google book search
  5. ^ JA Petro, Z. Niazi: Burn Reconstruction. In: Jeffrey Weinzweig: Plastic Surgery Secrets Plus. Chapter 103, Elsevier Health Sciences, 2010, ISBN 0-323-08590-3 limited preview in Google Book Search