Howell-Jolly corpuscles

A: Cabot ring
B: Howell-Jolly corpuscles

Howell-Jolly bodies (English Howell-Jolly bodies ) are pathological cell nucleus fragments in the normally nucleated erythrocytes that can occur in asplenia or in hemolytic and megaloblastic anemia. These nuclear residues consist of DNA residues and are normally removed from the erythrocytes when they pass through the endothelial fissures in the spleen. After a splenectomy or asplenia , Howell-Jolly bodies should be found in the blood smear . If this is not the case, this indicates the presence of an accessory spleen .

Individual evidence

1. ↑ Chapter Spleen In: Basic Textbook Internal Medicine 4th Edition, 2008, p. 305.

literature

• H. Renz-Polster , S. Krautzig (Hrsg.): Basic textbook internal medicine 4th edition. Elsevier, Munich 2008, ISBN 978-3-437-41053-6 .

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !