Inhibition Growth Concentration

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The Inhibition Growth Concentration ( IGC ) is a measure to describe the toxicity of a substance.

The Inhibition Growth Concentration 50 (IGC 50 , "growth inhibition concentration 50 ") determines the concentration of the toxic substance at which the examined cell growth is reduced by half (50%).

See also

literature

  • Mohammad Hossein Fatemi, Hanieh Malekzadeh: Prediction of Log (IGC 50 ) −1 for Benzene Derivatives to Ciliate Tetrahymena pyriformis from Their Molecular Descriptors. In: Bulletin of the Chemical Society of Japan. 83, 2010, pp. 233-245, doi : 10.1246 / bcsj.20090213 .
  • Juan A. Castillo-Garit, Yovani Marrero-Ponce, Jeanette Escobar, Francisco Torrens, Richard Rotondo: A novel approach to predict aquatic toxicity from molecular structure. In: Chemosphere . 73, 2008, pp. 415-427, doi : 10.1016 / j.chemosphere.2008.05.024 .