John R. Riordan

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John Richard Riordan OC (* 2 September 1943 in St. Stephen , New Brunswick ) is a Canadian biochemist who on cystic fibrosis research (Cystic fibrosis).

Life

Riordan received his bachelor's degree from the University of Toronto in 1966 , where he received his PhD in biochemistry in 1970. From 1970 to 1973 he was at the Max Planck Institute for Biophysics in Frankfurt am Main . From 1974 he was a professor at the University of Toronto. He is a professor at the University of North Carolina at Chapel Hill and has been a visiting scholar at the Salhgrenska Academy (of which he is an honorary doctor) and the University of Gothenburg.

In 1989 Riordan and colleagues discovered the gene for the protein CFTR ( Cystic Fibrosis Transmembrane Conductance Regulator ), which is defective in cystic fibrosis. In the following years he also explored its function as a chloride channel and its role in the regulation of other ion channels.

In 1992 he received the Gairdner Foundation International Award .

Web links

Individual evidence

  1. Birth and career data according to American Men and Women of Science , Thomson Gale 2004
  2. JR Riordan, JM Rommens, B. Kerem, N. Alon, R. Rozmahel, Z. Grzelczak, J. Zielenski, S. Lok, N. Plavsic, JL Chou, ML Drumm, MC Iannuzzi, FS Collins, and LC Tsui : "Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA." In: Science , Volume 245, 1989, pp. 1073-1080.