Keratoderma

Classification according to ICD-10
L85.1	Acquired keratosis palmoplantaris [Acquired keratoma palmoplantare]
L86	Keratoma in diseases classified elsewhere including: keratosis follicularis, xeroderma
Q82.8	Hereditary palmoplantar keratosis
ICD-10 online (WHO version 2019)

The term keratoderma refers to a cornification disorder ( hyperkeratosis ) affecting the skin .

This includes a variety of diseases that can be classified as follows:

Congenital forms

Hereditary palmoplantar keratoses

• Diffuse palmoplantar hyperkeratosis
• Focal palmoplantar hyperkeratosis
• Dotted palmoplantar keratoses
• Ectodermal dysplasia with palmoplantar hyperkeratosis
  • Papillon-Lefèvre syndrome (synonyms: Keratodermia palmo-plantaris diffusa Papillon-Lefèvre; Keratosis palmoplantaris diffusa with periodontopathy, Haim-Munk syndrome)
  • Naegeli syndrome (synonyms: Naegeli-Franceschetti-Jadassohn syndrome; NFJ syndrome)
  • Pachyonychia congenita
  • Focal palmoplantar and oral mucosal hyperkeratosis syndrome
  • Clouston syndrome (synonyms: hidrotic ectodermal dysplasia; ectodermal dysplasia II)
  • Schöpf-Schulz-Passarge syndrome (synonym: palmoplantar ectodermal dysplasia type XXIX)

• Syndromes with ectodermal dysplasia and palmoplantar hyperkeratosis
  • Naxos disease (synonyms: Naxos syndrome; palmoplantar keratosis with arrhythmogenic cardiomyopathy)
  • Wool hair-palmoplantar-dilated cardiomyopathy syndrome (Synonyms: Carvajal syndrome; Carvajal variant of Naxos syndrome; English Woolly hair-palmoplantar keratoderma dilated cardiomyopathy-syndrome)

• Unclassified forms
  • Non-epidermolytic palmoplantar keratosis (synonyms: Diffuse palmoplantar keratoderm type Norrbotten; NEPPK; palmoplantar keratosis, diffuse, autosomal dominant, type Norrbotten; PALMOPLANTAR KERATODERMA, BOTHNIAN TYPE; PPKB)
    • Kindler syndrome (synonyms: acrokeratotic poikiloderma; KS; poikilodermia type Kindler)
    • Dermatopathia pigmentosa reticularis

Erythrokeratoderma

Follicular hyperkeratosis

• Keratosis follicularis (synonyms: Keratosis pilaris)
  • Ulerythema ophryogenes (synonyms: Keratosis pilaris atrophicans faciei (KPAF), Folliculitis rubra)
• Keratosis pilaris (synonyms: Keratosis pilaris rubra atrophicans; Keratosis pilaris atrophicans)
  • Keratosis follicularis spinulosa decalvans
  • Atrophoderma vermiculatum (synonyms: Ulerythema acneiforme; Folliculitis ulerythematosa reticulata; English honeycomb atrophy)

Dyskeratotic-acantholytic keratoses

• Darier's disease (synonyms: keratosis follicularis; Darier disease; dyskeratosis follicularis Darier-White; Darier-White disease; dyskeratosis follicularis; dyskeratosis follicularis Darier; keratosis vegetans)
• Acrokeratosis verruciformis Hopf
• Pemphigus, benign chronic familial (synonyms: Hailey-Hailey's disease; chronic benign familial pemphigus) OMIM 169600

Porokeratoses

Keratoderma syndromes

• Palmoplantar Keratosis - Spastic Paralysis (Synonyms: Palmoplantar Hyperkeratosis-Spastic Paralysis Syndrome; Powell-Venencie-Gordon Syndrome)
• Stern-Lubinsky-Durrie syndrome (synonyms: Korneo-dermato-ossäres-Syndrom; English Corneodermatosseous syndrome)
• Cardio-Facio-Cutaneous Syndrome
• Bureau-Barrière-Thomas syndrome (synonyms: Keratodermia palmo-plantaris diffusa Bureau-Barrière-Thomas; Bureau-Barrière syndrome II)
• Hanhart syndrome (Synonyms: Keratodermia palmo-plantaris papulosa Hanhart; Keratosis plamo-plantaris with systematized lipomas)
• Helicotrichia keratosis syndrome (synonym: Keratodermia palmo-plantaris varians with helicotrichia)
• Gorlin syndrome (synonyms: basal cell nevus syndrome; NBCCS; naevoid basal cell carcinoma syndrome)
• CEDNIK syndrome (synonym: cerebral dysgenesis - neuropathy - ichthyosis - palmoplantar keratoderm)
• Cole's disease (synonyms: hypopigmentation and punctiform keratosis of the palms of the hands and soles of the feet; hypopigmentation-punctate palmoplantar keratoderma syndrome)
• Epidermolysis bullosa simplex due to plakophilin deficiency
• Epidermolysis bullosa simplex type Dowling-Meara
• Pityriasis rubra pilaris (synonym: Devergie disease)
• Incontinentia pigmenti ( Bloch-Sulzberger syndrome )
• Sjogren Larsson Syndrome

Acquired forms

• AIDS-associated keratoderma
• Arsenic-related keratosis
• Calluses
• Keratodermia climacterica Haxthausen (Synonym: Haxthausen Hyperkeratosis)
• Corns
• dermatitis
• Human papillomaviruses
• Keratoderma blenorrhagicum
• Lichen planus
• scabies
• Paraneoplastic keratoderma
• Psoriasis (psoriasis)
• Reactive arthritis (Reiter syndrome)
• syphilis
• Athlete's foot
• Sézary syndrome
• Tuberculosis verrucosa cutis
• Drug-Induced Keratoderma

See also

• Ichthyoses

literature

• Freedberg, et al. (2003): Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0 .

Individual evidence

1. ↑ ^{a b} Derma-net-online ( memento of the original from November 20, 2015 in the Internet Archive ) Info: The archive link was inserted automatically and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. 
2. ↑ ^{a b c d e} Bernfried Leiber (founder): The clinical syndromes. Syndromes, sequences and symptom complexes . Ed .: G. Burg, J. Kunze, D. Pongratz, PG Scheurlen, A. Schinzel, J. Spranger. 7., completely reworked. Edition. tape 2 : symptoms . Urban & Schwarzenberg, Munich et al. 1990, ISBN 3-541-01727-9 .
3. ^ Papillon-Lefèvre syndrome. In: Orphanet (Rare Disease Database).
4. ^ Naegeli-Franceschetti-Jadassohn syndrome. In: Orphanet (Rare Disease Database).
5. ↑ Pachyonychia congenita. In: Orphanet (Rare Disease Database).
6. ↑ G. Bethke, G. Kolde, G. Bethke, PA Reichart: [Focal palmoplantar and oral mucosa hyperkeratosis syndrome]. In: Oral and maxillofacial surgery: MKG. Vol. 5, No. 3, May 2001, pp. 202-205, doi: 10.1007 / s100060100306 , PMID 11432338 .
7. ↑ dysplasia, ectodermal hidrotic. In: Orphanet (Rare Disease Database).
8. ↑ Schöpf-Schulz-Passarge syndrome. In: Orphanet (Rare Disease Database).
9. ^ Naxos disease. In: Orphanet (Rare Disease Database).
10. ↑ Woolly hair-palmoplantar keratosis-dilated cardiomyopathy syndrome. In: Orphanet (Rare Disease Database).
11. ↑ Palmoplantar keratosis, nonepidermolytic. In: Orphanet (Rare Disease Database).
12. ↑ PPKB.  In: Online Mendelian Inheritance in Man . (English)
13. ^ Kindler syndrome. In: Orphanet (Rare Disease Database).
14. ↑ Dermatopathia pigmentosa reticularis. In: Orphanet (Rare Disease Database).
15. ↑ Keratosis pilaris.  In: Online Mendelian Inheritance in Man . (English)
16. ↑ lerythema Ophryogenes. In: Orphanet (Rare Disease Database).
17. ↑ KFSDX.  In: Online Mendelian Inheritance in Man . (English)
18. ↑ Keratosis follicularis spinulosa decalvans. In: Orphanet (Rare Disease Database).
19. ↑ Atrophoderma vermiculatum. In: Orphanet (Rare Disease Database).
20. ↑ ATROPHODERMA VERMICULATA.  In: Online Mendelian Inheritance in Man . (English)
21. ↑ Darier's disease. In: Orphanet (Rare Disease Database).
22. ↑ Pemphigus, benign chronic familial. In: Orphanet (Rare Disease Database).
23. ↑ Palmoplantar Keratosis - spastic paralysis. In: Orphanet (Rare Disease Database).
24. ^ Stern-Lubinsky-Durrie syndrome. In: Orphanet (Rare Disease Database).
25. ↑ Gorlin Syndrome. In: Orphanet (Rare Disease Database).
26. ↑ Cednik syndrome. In: Orphanet (Rare Disease Database).
27. ^ Cole's disease. In: Orphanet (Rare Disease Database).
28. ↑ Epidermolysis bullosa simplex due to plakophilin deficiency. In: Orphanet (Rare Disease Database).
29. ↑ Epidermolysis bullosa simplex type Dowling-Meara. In: Orphanet (Rare Disease Database).
30. ^ Pityriasis rubra pilaris. In: Orphanet (Rare Disease Database).
31. ↑ Rapini, Ronald P .; Bolognia, Jean L .; Jorizzo, Joseph L .: Dermatology: 2-Volume Set . Mosby, St. Louis 2007, ISBN 1-4160-2999-0 , p. 778.

Web links

• Medscape

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