Liver enzymes

The liver enzymes are a number of partially ubiquitous and partially liver-specific enzymes that occur in the body , the determination of which in the serum provides information about tissue damage to the liver . The most common parameters are glutamate oxaloacetate transaminase (GOT) or (according to the new nomenclature) aspartate aminotransferase (ASAT), glutamate pyruvate transaminase (GPT) or alanine aminotransferase (ALAT) and gamma-glutamyltransferase ( γ-GT). The quotient of ASAT and ALAT ( De-Ritis quotient ) provides information on the cellular damage, since ASAT occurs predominantly in mitochondria . Increases in liver enzymes can be reactions without disease value, for example as a side effect of medication, but can also point in the direction of severe functional disorders and cell death. A synopsis of other findings and the well-being of the person concerned is therefore essential for interpretation. In the case of liver damage in the context of liver inflammation , cancer , biliary stasis , but also in the case of poisoning and chronic alcohol abuse , the liver enzymes are almost always increased in a characteristic manner.