Lennart Hardell

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Lennart Hardell (born October 18, 1944 in Hietaniemi , Norrbotten County ) is a Swedish oncologist , cancer epidemiologist and environmental doctor.

Hardell studied medicine at Umeå University and received his doctorate in 1981. His dissertation ( Epidemiological studies on soft-tissue sarcoma and malignant lymphoma and their relation to phenoxy acid or chlorophenol exposure ) was an epidemiological study on cancer risks from chlorophenol derivatives, which are used as disinfectants, and salts of phenoxycarboxylic acids , which are used as herbicides . Hardell is Professor of Oncology and Cancer Epidemiology at Örebro University Hospital .

He is known for the study of potential cancer risks of artificial organic materials in the environment with epidemiological studies, including dioxins , insecticides , fungicides , herbicides such as glyphosate , PCBs and flame retardants tetrabromobisphenol A . He is also known for epidemiological studies on the risks of electromagnetic radiation from cell phone receivers and cordless phones for brain tumors ( acoustic neuroma , glioma ).

His investigations led to the ban on the herbicide with the Swedish brand name Hormoslyr in Sweden in 1977 . It was first marketed in the United States in 1944 (and was developed in the United States for wartime use in 1941 - it was used in the Korean War) as a forestry herbicide. It was also used as such by forest workers in Sweden from 1947 onwards. It contained 2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid and thus partly the same substances as Agent Orange, which is used as a defoliant in Vietnam (with a similar risk of dioxin contamination). In 1997, Hardell received the Swedish Miljömedicinska priset for his commitment in this context and for pioneering work on the cancer risk of similar substances from the dioxin environment.

In a study from 2002 he found an increased risk of non-Hodgkin lymphoma (and its variant hairy cell leukemia ) with glyphosate ( odds ratio OR = 3) and the herbicide MCPA (OR = 2.6). However, the studies were based on retrospective telephone interviews (cases from the cancer registry and the control group) and are based on the ability to remember and the respondents' assessment of contact with the substances in question.

In the case of cell phones, after reviewing other studies in 2007, he concluded that there was an increased risk of cancer and predicted a corresponding relative increase in cancer cases. This was followed in 2011 by a study that postulated an increased long-term risk of malignant tumors due to mobile phone use. A study by M. Little and colleagues from 2012 with data from the USA contradicted an upward trend in cancer cases predicted by the Swedish study. The evaluation of the studies is controversial, but the study by Hardell and colleagues from 2011, together with the Interphone study from 2010, led the WHO to determine a possible cancer risk from mobile phones (see also mobile phone studies on possible cancer development ). Hardell also appeared as an expert witness in lawsuits against cell phone companies, for example in the USA and Italy.

Fonts

Glyphosate:

  • L. Hardell, M. Eriksson, M. Nordstrom: Exposure to pesticides as risk factor for non-Hodgkin's lymphoma and hairy cell leukemia: pooled analysis of two Swedish case-control studies, Leuk. Lymphoma, Vol. 43, 2002, pp. 1043-1049, PMID 12148884 .

Cellular Risks:

  • L. Hardell, KH Mild, M. Carlberg: Case-control study on the use of cellular and cordless phones and the risk for malignant brain tumors, Int J Radiat Biol. Volume 78, 2002, pp. 931-936. PMID 12465658 .
  • L. Hardell, M. Carlberg, KH Mild: Case-control study of the association between the use of cellular and cordless telephones and malignant brain tumors diagnosed during 2000–2003, Environ Res. Volume 100, 2006, pp. 232–241. PMID 16023098 .
  • L. Hardell, M. Carlberg: Mobile phones, cordless phones and the risk for brain tumors, Int. J. Oncol., Vol. 35, 2009, pp. 5-17. PMID 19513546 .
  • L. Hardell, M. Carlberg, MK Hansson: Pooled analysis of case-control studies on malignant brain tumors and the use of mobile and cordless phones including living and deceased subjects, Int J Oncol. Volume 38, 2011, pp. 1465-1474, PMID 21331446 .
  • L. Hardell, M. Carlberg, MK Hansson: Re-analysis of risk for glioma in relation to mobile telephone use: comparison with the results of the Interphone international case-control study, Int J Epidemiol. Volume 40, 2011, pp. 1126-1128.
  • L. Hardell, M. Carlbeg, F. Söderqvist, KH Mild, Pooled analysis of case-control studies on acoustic neuroma diagnosed 1997–2003 and 2007–2009 and use of mobile and cordless phones., International Journal of Oncology, Volume 43, 2013, pp. 1036-1044, PMID 23877578 .

Web links

Individual evidence

  1. Hardell's blog on Hormoslyr, Swedish
  2. L. Hardell, M. Carlberg, F. Söderqvist, KH Mild, LL Morgan, Long-term use of cellular phones and brain tumors: increased risk associated with use for> = 10 years, Occupational and Environmental Medicine, Volume 64, 2007 , Pp. 626-632, PMID 17409179 .
  3. z. BM Little et al. a .: Mobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United States, British Medical Journal, Volume 344, 2012, pp. 1147–1147, doi: 10.1136 / bmj.e1147