Lymphocyte selectin
| L-selectin | ||
|---|---|---|
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| according to PDB 1KJB | ||
| other names |
CD62 antigen-like family member L, leukocyte adhesion molecule 1, LAM-1 |
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| Properties of human protein | ||
| Mass / length primary structure | 372 amino acids , 42,187 Da | |
| Identifier | ||
| External IDs | ||
| Orthologue (human) | ||
| Entrez | 6402 | |
| Ensemble | ENSG00000188404 | |
| UniProt | P14151 | |
| Refseq (mRNA) | NM_000655.4 | |
| Refseq (protein) | NP_000646.2 | |
| PubMed search |
6402
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L-selectin (synonym L-selectin , CD62L ) is a surface protein from the group of selectins .
properties
L-selectin is a lectin and participates in the cell adhesion of lymphocytes (B and T) in an immune reaction . It mediates cell contacts between lymphocytes and endothelial cells in lymph nodes . It is involved in the rolling of the lymphocytes along the cell surfaces. L-selectin is glycosylated .
Web links
Individual evidence
- ↑ S. Wedepohl, F. Beceren-Brown, S. Riese, K. Buscher, S. Enders, G. Bernhard, K., Kilian, V. Blanchard, J. Dernedde, R. Tauber: L-selectin-a dynamic regulator of leukocyte migration. In: European journal of cell biology. Volume 91, Number 4, April 2012, pp. 257-264, doi : 10.1016 / j.ejcb.2011.02.007 , PMID 21546114 .