Meigs syndrome

from Wikipedia, the free encyclopedia
Classification according to ICD-10
D27 Benign neoplasm of the ovary
ICD-10 online (WHO version 2019)

As Meigs' syndrome (named after Joe Vincent Meigs is) in the gynecology of the simultaneous occurrence fibroma of the ovary (ovary), an ascites and a pleural effusion mentioned. Fibromas are benign tumors. In a Ascites is an accumulation of fluid in the free abdominal cavity between the organs and a pleural effusion to an accumulation of fluid in the pleural cavity , i.e. between the two leaves of the pleura ( pleura ). The syndrome was named after the American gynecologist Joe Vincent Meigs, who first described the disease in 1954.

The exact mechanisms for the development of ascites are not yet fully understood. The pleural effusion is a result of exudate or ascites. The fluid moves from the abdominal cavity to the pleural cavity through congenital defects in the diaphragm . Meigs already recognized this. Meigs syndrome can be completely cured by removing the tumor, usually completely removing the affected ovary, called an ovariectomy . The accumulations of fluid are absorbed by the surrounding tissue.

Ascites and pleural effusion can also develop in other diseases of the ovary, such as degenerative changes, a teratoma, and ovarian hyperstimulation syndrome . The respective clinical pictures are then referred to as pseudo-Meigs syndrome .


  • DM McGee et al .: Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-2003. A 10-year-old girl with recurrent bouts of abdominal pain. In: N Engl J Med. 2003 Jul 31; 349 (5), pp. 486-494. PMID 12890848

Individual evidence

  1. Berthold Jany, Tobias Welte: Pleural effusion in adults - causes, diagnosis and therapy. In: Deutsches Ärzteblatt. Volume 116, No. 21, 2019, pp. 377-385, p. 379.