Mitsuhashi Susumu

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Mitsuhashi Susumu ( Japanese 三橋 進 ; born October 26, 1917 Chiba Prefecture ; † September 1, 1997 ) was a Japanese microbiologist and biochemist . He is known for research on the antibiotic resistance of bacteria and their transferability through gene (plasmid) exchange.

He was a professor at Gunma University Medical School in Maebashi .

In 1960, independently of Tsotumu Watanabe , he discovered transferable resistance to various antibiotics in bacteria (in Salmonella with bacteriophages and later in E. coli ). In Japan, multiple resistances to antibiotics were observed in Shigella in the early 1950s and transmission of E. coli was suspected and proven (Akiba et al. 1960, Ochiai et al. 1959). Mitsuhashi called the transferred factors resistance factors or R-factors, a name that is now obsolete after being identified with plasmids .

In 1981 he received the Paul Ehrlich and Ludwig Darmstaedter Prize .

Fonts

  • Published in: Transferable drug resistance factor R , Tokyo University Press 1971
  • Editor with Hajime Hashimoto: Microbiological drug resistance , 2 volumes, Baltimore, University Park Press 1975, 1979
  • Published in: Aminoglycoside Antibiotics , Baltimore, University Park Press 1975
  • Editors: Macrolide antibiotics and lincomycin , Baltimore, University Park Press 1971
  • Editor: R factor. Drug resistance plasmide , Baltimore, University Park Press 1977
  • Publisher beta-lactam antibiotics , Japan Scientific Societies Press 1981
  • Editor with Ladislav Rosival, V. Krčméry: Antibiotic resistance: transposition and other elements , Avicenium 1980
  • same (editors): plasmids. Medical and theoretical aspects , Avicenium 1977

Individual evidence

  1. 三橋 進 . In: デ ジ タ ル 版 日本人 名 大 辞典 + Plus at kotobank.jp. January 20, 2009, accessed March 6, 2012 (Japanese, online version by Nihon Jinmei Daijiten . Kodansha).