Nifoxipam

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Structural formula
Structural formula of nifoxipam
General
Surname Nifoxipam
other names
  • 3-hydroxy-desmethylflunitrazepam
  • 5- (2-fluorophenyl) -3-hydroxy-7-nitro-1,3-dihydro-2 H -1,4-benzodiazepin-2-one
  • 5- (2-Fluorophenyl) -3-hydroxy-7-nitro-1 H -benzo [1,4] diazepin-2 (3 H ) -one
  • DP370
Molecular formula C 15 H 10 FN 3 O 4
Brief description

crystalline solid

External identifiers / databases
CAS number 74723-10-7
PubChem 3058221
ChemSpider 2319383
Wikidata Q20743749
properties
Molar mass 315.26 g mol −1
safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Nifoxipam is a chemical compound from the benzodiazepine group and a metabolite of flunitrazepam . The compound has been marketed as a research chemical since 2014 .

Nifoxipam can be identified by gas chromatography with mass spectrometry coupling . The compound showed a tranquillizing (fight test) and a sleep-prolonging effect with a significantly lower toxicity than comparison substances.

Individual evidence

  1. ↑ a b c Maria Katselou, Ioannis Papoutsis, Panagiota Nikolaou, Chara Spiliopoulou, Sotiris Athanaselis: Metabolites replace the parent drug in the drug arena. The cases of fonazepam and nifoxipam. In: Forensic Toxicology. 35, 2017, p. 1, doi : 10.1007 / s11419-016-0338-5 .
  2. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  3. ↑ Google patent search: Patent EP0158267A2 - Medicines containing 5- (2-fluorophenyl) -1,3-dihydro-3-hydroxy-7-nitro ... - Google patent search , accessed on August 30, 2017.