Oncocytoma

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Oncocytoma of Gl. submandibularis
Oncocytoma of the kidney
Oncocytoma of the right kidney (on the left in the picture) in the computed tomography with wheel spoke phenomenon. The Hypodensity is not a classic criterion of Onkozytoms.

In oncocytomas is a group of benign epithelial tumors that histologically the structure of fine-grained, large, eosinophilic mitochondria-rich tumor cells called oncocytes ( "Hürthle cells") have in common.

Oncocytomas occur in the salivary glands , kidney , adenohypophysis, and thyroid gland . In the latter localization in particular, the tumor is also referred to as Hürthle cell adenoma according to the physiologist Karl Hürthle .

Diagnosis

The oncocytoma of the kidney is occasionally discovered by chance on computed tomography . Differentiating it from a malignant tumor such as renal cell carcinoma is often not easy in imaging, even if characteristics such as a central scar or a so-called wheel spoke phenomenon have been described.

Individual evidence

  1. ↑ Choudhary et al .: Renal oncocytoma: CT features cannot reliably distinguish oncocytoma from other renal neoplasms. Clin Radiol. 2009; 64 (5): 517-22. PMID 19348848

literature

  • Eiss et al. Renal oncocytoma: CT diagnostic criteria revisited J Radiol. 2005 Dec; 86 (12 Pt 1): 1773-82. PMID 16333226
  • Radopoulos et al. A rare case of renal oncocytoma associated with erythrocytosis: case report. BMC Urol. 2006 Sep 23; 6:26. PMID 16995951
  • Kosuda et al. Iodine-131 therapy for parotid oncocytoma. J Nucl Med. 1988 Jun; 29 (6): 1126-9. PMID 3373321