Panniculitis
| Classification according to ICD-10 | |
|---|---|
| M79.3 | Panniculitis, unspecified |
| ICD-10 online (WHO version 2019) | |
As panniculitis or panniculitis (from latin panniculus , Lobe ', as diminutive of pannus ) is a localized inflammation of the subcutaneous adipose tissue , respectively. It is a descriptive clinical term that does not yet provide any information about the cause of its development. In the past, panniculitis was considered to be "fibrositis" and thus a form of "soft tissue rheumatism" of subcutaneous adipose tissue.
classification
The panniculitides are divided into septal / lobular, as well as with and without accompanying vasculitis. Lobular refers to the adipocytes themselves, septal refers to an inflammation in the connective tissue septa separating the individual adipocyte globules.
Septal, without vasculitis
This is the most common type of panniculitis. The most common diagnosis here is erythema nodosum, which occurs in some infectious diseases (e.g. streptococcal infections) and autoimmune diseases (typically sarcoid as part of Löfgren's syndrome ) . Other forms of septal panniculitis without vasculitis can occur in scleroderma or necrobiosis lipoidica .
Septal, with vasculitis
Occurrence in polyarteritis nodosa or thrombophlebitis.
Lobar, without vasculitis
Occurrence in pancreatic panniculitis (pancreatic enzymes break down fats and thus cause inflammatory processes. Typically, blisters can be recognized histologically through saponification processes.) In the context of acute or chronic pancreatitis, alpha-1 antitrypsin deficiency or lupus erythematosus profundus.
The cold panniculitis is a few weeks lasting appearance after severe cold.
Lobar, with vasculitis
Examples are erythema induratum or calciphylaxis .
Diagnosis
Often, punch biopsies are not sufficient because they do not gain enough subcutaneous fatty tissue (subcutis). A section biopsy must therefore often be performed. Typical changes can then be recognized either in the connective tissue septa of the subcutis or within the lobules.
A Pannikulitis type Rothmann-Makai (Syn .: Lipogranulomatosis subcutanea ) develops only after years spontaneously.
A recurrent panniculitis may, at the Pfeiffer-Weber-Christian disease (as recurrent non-suppurative panniculitis also Weber Christiansche disease occur called).
Web links
- Youtube lecture on panniculitis by Clay J. Cockerell (2015, in English)
Individual evidence
- ↑ Ludwig Heilmeyer , Wolfgang Müller: The rheumatic diseases. In: Ludwig Heilmeyer (ed.): Textbook of internal medicine. Springer-Verlag, Berlin / Göttingen / Heidelberg 1955; 2nd edition ibid. 1961, pp. 309–351, here: pp. 342–346: The soft tissue rheumatism (fibrositis, muscular rheumatism, myalgia, panniculitis).
- ↑ Ludwig Heilmeyer, Wolfgang Müller: The rheumatic diseases. 1961, p. 344 f.
