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Pathophysiology or pathological physiology is conceptually made up of the components pathology and physiology . In it, the pathology is the study of the pathological changes in the body of a living being and the physiology is the study of the functioning of the body (gr. Physis) of a living being.

The conceptual combination of “pathophysiology” means how the body functions differently under the pathological changes and which functional mechanisms lead to the pathological change ( pathogenesis ). It is accepted that even a pathological change still has a certain (physiologically meaningful) normal function, in that the physiological balance of the organism is maintained ( homeostasis ). This fact is of decisive importance for the diagnosis , since it assumes a continuum between healthy and sick, in which normal life processes (still) take place, and not from a strict distinction between healthy and sick.

See also


  • Ludolf Krehl : Pathological Physiology. 11th edition. Leipzig 1921.
  • Siegfried Schwarz, Othmar Förster, Meinrad Peterlik, Konrad Schauenstein, Georg Wick (eds.): Pathophysiology. Molecular, cellular, systemic basis of diseases. Maudrich, Vienna 2007, ISBN 3-85175-860-9 .
  • Walter Siegenthaler , Hubert E. Blum (Ed.): Clinical Pathophysiology. 9th, completely revised edition. Thieme, Stuttgart a. a. 2006, ISBN 3-13-449609-7 .
  • Stefan Silbernagl , Florian Lang: Pocket Atlas Pathophysiology. 3rd, completely revised and expanded edition. Thieme, Stuttgart a. a. 2009, ISBN 978-3-13-102193-9 .

Individual evidence

  1. Thure von Uexküll : Basic questions of psychosomatic medicine (= rowohlts German encyclopedia . 179/180, ZDB -ID 985674-2 ). Rowohlt, Reinbek near Hamburg 1963, p. 128.