Porcine proliferative enteritis

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The Porcine proliferative enteritis (PPE) is a complex of several diseases of the pig , all of a proliferating inflammation of the mucosa of the small intestine have in common and the bacterium Lawsonia intracellularis caused.

Pathogen

The main causative agent of the PPE complex is Lawsonia intracellularis from the genus Lawsonia . Furthermore, Campylobacter hyointestinalis , Campylobacter hyoilei and Campylobacter mucosalis from the genus Campylobacter were detected, whose involvement in the disease is still unclear.

Clinic and Pathology

There are several clinical pictures, which also have different names:

  • Necrotizing Enteritis (NE): develops from the PIA; the thickenings develop into coagulation necrosis
  • Porcine intestinal adenomatosis (PIA): thickening and wrinkling of the intestinal mucosa
  • Proliferative Hemorrhagic Enteritis (PHE): blood clots develop in the intestinal contents; Fever and sudden death
  • Regional enteritis (RE): a single section thickens greatly and becomes rigid; Risk of intestinal rupture

The disease mainly affects pigs from 6 to 20 weeks old. The diarrheal faeces are poorly digested and in PHE it is reddish-dark because of the blood. The chronic course leads to grief and loss of performance.

Diagnosis

In addition to the clinical and pathological-anatomical picture, various laboratory diagnostic methods are used for diagnosis. The pathogen is detected by bacteriological examination , polymerase chain reaction , the indirect by serum antibody detection with immunofluorescence or enzyme-linked immunosorbent assay .

therapy

For therapy are antibiotics such as chlortetracycline , tylosin , lincomycin , esters of lincomycin spectinomycin , neomycin , tiamulin and valnemulin used. Vaccination therapy with live vaccines is also advisable. Good hygiene management prevents the disease.

literature

  • M. Rolle and A. Mayr: Medical microbiology, infection and epidemic studies. Enke Verlag, Stuttgart 2007 ISBN 9783830410607

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