Prinzmetal's angina

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Classification according to ICD-10
I20.1 Angina pectoris with proven coronary spasm
ICD-10 online (WHO version 2019)

The variant angina (synonyms: Variant angina , variant angina pectoris , angina varians ), named after its first description in 1959, Myron Prinzmetal (1908-1987), is a special form of angina is assuming a temporary circulatory disorder (. Ischemia ) of the heart muscle ( Myocards ) caused by a spasm ( vasospasm ) in one or more of the coronary arteries .

The duration of such a violent heartache is between seconds and minutes. It occurs regardless of stress, especially in the early morning hours. The worst consequence of prolonged ischemia can be a heart attack .

Reversible ST elevations in the ECG in the absence of an increase in troponin and CK are diagnostic . The treatment is carried out with nitrates and calcium antagonists . Beta blockers are contraindicated . The disease manifests itself mainly in the 3rd to 4th Decade of life. Above all, heavy smokers and, as in the angina pectoris vasomotorica described by Reindell and Klepzig, younger people are at risk (women are just as frequently affected as men).

literature

  • M. Prinzmetal, R. Kennamer, R. Merliss: A variant form of angina pectoris. In: Am J Med. 1959; 27, pp. 375-388. PMID 14434946 .

Individual evidence

  1. ↑ Reinhard Larsen: Anesthesia and intensive medicine in cardiac, thoracic and vascular surgery. (1st edition 1986) 5th edition. Springer, Berlin / Heidelberg / New York et al. 1999, ISBN 3-540-65024-5 , p. 181 (there divided into two groups: without and with highly fixed obstruction).
  2. ↑ a b Netters internal medicine, 2nd completely revised and updated edition. Georg Thieme Publishing House. 2014. p. 36
  3. ^ Herbert Reindell , Helmut Klepzig: Diseases of the heart and the vessels. In: Ludwig Heilmeyer (ed.): Textbook of internal medicine. Springer-Verlag, Berlin / Göttingen / Heidelberg 1955; 2nd edition ibid. 1961, pp. 450-598, here: pp. 554 f.

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