Pseudohyponatremia

When pseudohyponatraemia is a measuring technology, low sodium concentration.

Pathophysiology

The sodium is only found in the aqueous part of the serum . It is not found in proteins and lipids . The standard methods for determining the sodium concentration, such as flame photometric or indirect ion-selective measurement, result in incorrectly low sodium values ​​at high lipid or protein concentrations.

causes

• Hyperlipoproteinemia
• Hyperproteinemia ( multiple myeloma , Waldenström's disease )

literature

• R. Rosenthal et al.: Pseudohyponatremia. In: Switzerland Med Wochenschr. 2000; 130, p. 161 (pdf)
• HG Worth: Plasma sodium concentration: bearer of false prophecies? In: Br Med J (Clin Res Ed). 1983 Aug 27; 287 (6392), pp. 567-568. PMID 6411226

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