SMURF1

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SMURF1
other names

SMAD Specific E3 Ubiquitin Protein Ligase 1; SMAD-Specific E3 Ubiquitin Protein Ligase 1; HSMURF1; Smad Ubiquitination Regulatory Factor 1; SMAD Ubiquitination Regulatory Factor 1; Smad-Specific E3 Ubiquitin Ligase 1; E3 ubiquitin protein ligase SMURF1; E3 ubiquitin ligase SMURF1; EC 6.3.2.-; KIAA1625; EC 6.3.2

Existing structural data : 2LAZ , 2LB0 , 2LB1 , 2LTX , 3PYC

Properties of human protein
Mass / length primary structure 757 amino acids, 86114 Da
Identifier
External IDs
Orthologue
human House mouse
Entrez 57154 75788
UniProt Q9HCE7 Q9CUN6
PubMed search 57154 75788

SMURF1 is a ubiquitin protein ligase that adds the protein ubiquitin to SMAD proteins .

Individual evidence

  1. ↑ Y. Cao, L. Zhang: A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks. In: Cell Mol Life Sci. Volume 70, Issue 13, 2013, pp. 2305-2317. doi: 10.1007 / s00018-012-1170-7 . PMID 23007848 .