SMURF2

from Wikipedia, the free encyclopedia
SMURF2
other names

SMAD Specific E3 Ubiquitin Protein Ligase 2; SMAD-Specific E3 Ubiquitin Protein Ligase 2; SMAD Ubiquitination Regulatory Factor 2; HSMURF2; E3 ubiquitin protein ligase SMURF2; E3 ubiquitin ligase SMURF2; EC 6.3.2.-; EC 6.3.2

Existing structural data : 1ZVD , 2DJY , 2JQZ , 2KXQ , 2LTZ

Properties of human protein
Mass / length primary structure 748 amino acids, 86196 Da
Identifier
External IDs
Orthologue
human House mouse
Entrez 64750 66313
UniProt Q9HAU4 A2A5Z6
PubMed search 64750 66313

Smurf2 is a ubiquitin-protein ligases that SMAD proteins provides the protein with ubiquitin.

Individual evidence

  1. ↑ D. David, SA Nair, MR Pillai: Smurf E3 ubiquitin ligases at the cross roads of oncogenesis and tumor suppression. In: Biochim Biophys Acta. Volume 1835, Issue 1, 2013, pp. 119–128. doi: 10.1016 / j.bbcan.2012.11.003 . PMID 23164545 .